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We investigated the spatial distribution of kidney disease in the industrially contaminated site of Taranto.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cases were subjects with a first hospital discharge diagnosis of kidney disease. Cases affected by specific comorbidities were excluded. Standardized Hospitalization Ratios (SHRs) were computed for low\/high exposure area and for modeled spatial distribution of cadmium and fine particulate matter.<\/jats:p><\/jats:sec><jats:sec><jats:title>Result<\/jats:title><jats:p>Using the high\/low exposure approach, in subjects aged 20\u201059 years residing in the high exposure area a significant excess of hospitalization was observed in males and a non\u2010significant excess in females. No excesses were observed in subjects aged 60 years and over. The analysis by the modeling approach did not show a significant association with the greatest pollution impact area.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Due to the excesses of hospitalization observed in the high\/low exposure approach, a continuing epidemiological surveillance of residents and occupational groups is warranted.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.22781","type":"journal-article","created":{"date-parts":[[2017,10,13]],"date-time":"2017-10-13T08:33:14Z","timestamp":1507883594000},"page":"1088-1099","source":"Crossref","is-referenced-by-count":4,"title":["Spatial distribution of kidney disease in the contaminated site of Taranto (Italy)"],"prefix":"10.1002","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6137-6568","authenticated-orcid":false,"given":"Marta","family":"Benedetti","sequence":"first","affiliation":[{"name":"Department of Environment and Health (DAMSA) Istituto Superiore di Sanit\u00e0 Rome 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