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This literature review and clinical case report about a 45\u2010year\u2010old man with no family history of motor neuron disease who developed overt symptoms of a neuromuscular disorder in close temporal association with his unwitting occupational exposure to volatile organic compounds (VOCs) puts forth the hypothesis that exposure to VOCs such as toluene, which disrupt motor function and increase oxidative stress, can unmask latent ALS type neuromuscular disorder in susceptible individuals.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.22791","type":"journal-article","created":{"date-parts":[[2017,11,10]],"date-time":"2017-11-10T11:27:25Z","timestamp":1510313245000},"page":"251-260","source":"Crossref","is-referenced-by-count":14,"title":["Amyotrophic lateral sclerosis\u2014A case report and mechanistic review of the association with toluene and other volatile organic compounds"],"prefix":"10.1002","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5508-3267","authenticated-orcid":false,"given":"Marcia H.","family":"Ratner","sequence":"first","affiliation":[{"name":"Department of Pharmacology and Experimental Therapeutics Boston University School of Medicine Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joe F.","family":"Jabre","sequence":"additional","affiliation":[{"name":"Department of Neurology David Geffen School of Medicine at UCLA Los Angeles California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William M.","family":"Ewing","sequence":"additional","affiliation":[{"name":"Compass Environmental, Inc. 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