{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T20:54:19Z","timestamp":1760043259707},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,2,14]],"date-time":"2019-02-14T00:00:00Z","timestamp":1550102400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Grant-in-Aid for the Promotion of joint International Research from Japan Society for the Promotion of Science","award":["15KK0316","15KK0316"],"award-info":[{"award-number":["15KK0316","15KK0316"]}]},{"name":"Grants-in-Aid for Scientific Research","award":["B20390182","B23390357","C20591737","C20591774 C22591639"],"award-info":[{"award-number":["B20390182","B23390357","C20591737","C20591774 C22591639"]}]},{"name":"Young Scientists","award":["A18689031"],"award-info":[{"award-number":["A18689031"]}]},{"name":"Exploratory Research from the Japanese Ministry of Education, Culture, Sports, Science and Technology","award":["19659305"],"award-info":[{"award-number":["19659305"]}]},{"name":"Grants-in-Aid from the Ministry of Health, Labour and Welfare","award":["H17-Men-eki-009","H18-Choujyu-037","H20-Choujyu-009"],"award-info":[{"award-number":["H17-Men-eki-009","H18-Choujyu-037","H20-Choujyu-009"]}]},{"name":"Research Aid from the Japanese Orthopaedic Association","award":["2006-1","2010-2"],"award-info":[{"award-number":["2006-1","2010-2"]}]},{"name":"A grant from the Japanese Orthopaedics and Traumatology Foundation, Inc.","award":["166"],"award-info":[{"award-number":["166"]}]},{"name":"The 2012 Wakayama Medical Award for Young Researchers"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>To explore the association of MRI\u2010diagnosed severe lumbar spinal stenosis with occupation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Occupational data were collected by questionnaire and all participants underwent spine MRI scans using the same protocol. Central lumbar spinal stenosis (LSS) was graded qualitatively. Those with severe LSS (&gt;two\u2010thirds narrowing) were compared with the controls with lesser degrees of stenosis or no stenosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Data were available for 722 subjects, mean age 70.1 years. 239 (33%) cases with severe LSS were identified. Factory\/construction workers had an almost four\u2010fold increased risk of severe LSS after adjustment for age, sex, smoking, and walking speed amongst those aged &lt;75 years (OR 3.97, 95%CI 1.46\u201010.85). Severe LSS was also associated with squatting \u22651\u2009h\/day (OR 1.76, 95%CI 1.01\u20103.07) but this association became non\u2010significant after adjustment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Further research is needed but this study adds more evidence that occupational factors are associated with an increased risk and\/or severity of degenerative disease of the lumbar spine.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.22957","type":"journal-article","created":{"date-parts":[[2019,2,14]],"date-time":"2019-02-14T13:46:15Z","timestamp":1550151975000},"page":"430-438","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Factory and construction work is associated with an increased risk of severe lumbar spinal stenosis on MRI: A case control analysis within the wakayama spine study"],"prefix":"10.1002","volume":"62","author":[{"given":"Yuyu","family":"Ishimoto","sequence":"first","affiliation":[{"name":"MRC Lifecourse Epidemiology Unit Southampton General Hospital Southampton Hampshire United Kingdom"},{"name":"Orthopedic surgery Wakayama Medical University Wakayama city Wakayama prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cyrus","family":"Cooper","sequence":"additional","affiliation":[{"name":"MRC Lifecourse Epidemiology Unit Southampton General Hospital Southampton Hampshire United Kingdom"},{"name":"Arthritis Research UK\/MRC Centre for Musculoskeletal Work and Health Southampton General Hospital Southampton Hampshire United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgia","family":"Ntani","sequence":"additional","affiliation":[{"name":"MRC Lifecourse Epidemiology Unit Southampton General Hospital Southampton Hampshire United Kingdom"},{"name":"Arthritis Research UK\/MRC Centre for Musculoskeletal Work and Health Southampton General Hospital Southampton Hampshire United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Yamada","sequence":"additional","affiliation":[{"name":"Orthopedic surgery Wakayama Medical University Wakayama city Wakayama prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Hashizume","sequence":"additional","affiliation":[{"name":"Orthopedic surgery Wakayama Medical University Wakayama city Wakayama prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiji","family":"Nagata","sequence":"additional","affiliation":[{"name":"Orthopedic surgery Wakayama Medical University Wakayama city Wakayama prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeyuki","family":"Muraki","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Department of Preventive Medicine for Locomotive Organ Disorders 22nd Century Medical &amp; Research Center University of Tokyo Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sakae","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Sensory and Motor System Medicine Graduate School of Medicine University of Tokyo Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriko","family":"Yoshimura","sequence":"additional","affiliation":[{"name":"Department of Joint Disease Research 22nd Century Medical and Research Center University of Tokyo Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Munehito","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Orthopedic surgery Wakayama Medical University Wakayama city Wakayama prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Walker\u2010Bone","sequence":"additional","affiliation":[{"name":"MRC Lifecourse Epidemiology Unit Southampton General Hospital Southampton Hampshire United Kingdom"},{"name":"Arthritis Research UK\/MRC Centre for Musculoskeletal Work and Health Southampton General Hospital Southampton Hampshire United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,2,14]]},"reference":[{"key":"e_1_2_12_2_1","first-page":"249","article-title":"Rheumatism in coal miners. III. Occupational factors","volume":"12","author":"Lawrence JS","year":"1955","journal-title":"Br J Ind Med"},{"key":"e_1_2_12_3_1","first-page":"420","article-title":"Occupational arthropathy: evidence from the past","volume":"46","author":"Waldron HA","year":"1989","journal-title":"Br J Ind Med"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780210206"},{"key":"e_1_2_12_5_1","first-page":"157","article-title":"Risk factors for knee osteoarthritis in Japanese women: heavy weight, previous joint injuries, and occupational activities","volume":"31","author":"Yoshimura N","year":"2004","journal-title":"J Rheumatol"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.2006.032409"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.304.6837.1269"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-017-4355-y"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.24514"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1053\/joca.1999.0274"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/s10165-005-0450-6"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.1855"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/32.10.911"},{"key":"e_1_2_12_14_1","first-page":"1","article-title":"Epidemiological differences between localised and non\u2010localised low back pain","volume":"42","author":"Coggon D","year":"2016","journal-title":"Spine (PhilaPa 1976)"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00420-016-1166-y"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-011587"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2007.07.392"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp0708097"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1833"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.338"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1996.tb00915.x"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002517-199306040-00002"},{"key":"e_1_2_12_23_1","first-page":"303","article-title":"MRI and myelography in the diagnosis of lumbar canal stenosis and disc herniation. A comparative study","volume":"104","author":"Jia LS","year":"1991","journal-title":"Chin Med J (Engl)"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyp276"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2012.06.018"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-12-175"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.14444\/2008"},{"key":"e_1_2_12_28_1","first-page":"20","article-title":"Trends in retirement age in four countries, 1965\u20131995","volume":"121","author":"Gendell M","year":"1998","journal-title":"Mon Labor Rev"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2015.04.015"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-14-219"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1539\/joh.48.69"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.2076"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.679"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-005-0036-1"}],"container-title":["American Journal of Industrial Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajim.22957","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajim.22957","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ajim.22957","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajim.22957","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T13:29:33Z","timestamp":1694179773000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajim.22957"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,14]]},"references-count":33,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1002\/ajim.22957"],"URL":"https:\/\/doi.org\/10.1002\/ajim.22957","archive":["Portico"],"relation":{},"ISSN":["0271-3586","1097-0274"],"issn-type":[{"value":"0271-3586","type":"print"},{"value":"1097-0274","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,14]]},"assertion":[{"value":"2018-12-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}