{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T09:03:10Z","timestamp":1758704590943,"version":"3.37.3"},"reference-count":28,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T00:00:00Z","timestamp":1564099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004497","name":"Onderzoeksraad, KU Leuven","doi-asserted-by":"publisher","award":["C2 project funding (C24\/18\/085)"],"award-info":[{"award-number":["C2 project funding (C24\/18\/085)"]}],"id":[{"id":"10.13039\/501100004497","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Associations between sarcoidosis or sarcoid\u2010like granulomatous lung disease and exposure to silica and other inorganic agents have been suggested in several studies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Cases<\/jats:title><jats:p>We describe granulomatous lung disease in two workers of a small production unit making metal\u2010halide lamps. Initially, both were diagnosed with sarcoidosis. However, in both men, birefringent particles were observed in the lung or mediastinal lymph node biopsies. Clipping of glass tubes led to moderate exposure to dust, consisting mainly of amorphous fused silica, with some cristobalite. After removal from exposure, both subjects improved clinically, radiologically, and functionally.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present cases support the hypothesis that silica might be a trigger for sarcoid\u2010like granulomatous lung disease. Sarcoidosis should be considered a diagnosis of exclusion and clinicians should carefully collect occupational and environmental exposure histories to identify workplace triggers.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.23030","type":"journal-article","created":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T09:16:24Z","timestamp":1564132584000},"page":"908-913","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Granulomatous lung disease in two workers making light bulbs"],"prefix":"10.1002","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6767-2691","authenticated-orcid":false,"given":"Steven","family":"Ronsmans","sequence":"first","affiliation":[{"name":"Department of Pulmonary Medicine, Clinic of Occupational and Environmental Medicine University Hospitals Leuven  Leuven Belgium"},{"name":"Department of Public Health and Primary Care, Centre for Environment and Health University of Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric K","family":"Verbeken","sequence":"additional","affiliation":[{"name":"Department of Pathology University Hospitals Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Els","family":"Adams","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Clinic of Occupational and Environmental Medicine University Hospitals Leuven  Leuven Belgium"},{"name":"IDEWE External Service for Prevention and Protection at Work  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Keirsbilck","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Clinic of Occupational and Environmental Medicine University Hospitals Leuven  Leuven Belgium"},{"name":"IDEWE External Service for Prevention and Protection at Work  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonas","family":"Yserbyt","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Unit for Interstitial Lung Diseases University Hospitals Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9648-3497","authenticated-orcid":false,"given":"Wim A","family":"Wuyts","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Unit for Interstitial Lung Diseases University Hospitals Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1528-526X","authenticated-orcid":false,"given":"Rudy","family":"Swennen","sequence":"additional","affiliation":[{"name":"Department of Earth and Environmental Science, Geology University of Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0292-6603","authenticated-orcid":false,"given":"Peter HM","family":"Hoet","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary Care, Centre for Environment and Health University of Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0571-4689","authenticated-orcid":false,"given":"Benoit","family":"Nemery","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Clinic of Occupational and Environmental Medicine University Hospitals Leuven  Leuven Belgium"},{"name":"Department of Public Health and Primary Care, Centre for Environment and Health University of Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,7,26]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_9_1_2_1","DOI":"10.1016\/S0140-6736(13)60680-7"},{"issue":"2","key":"e_1_2_9_1_3_1","first-page":"149","article-title":"ATS\/ERS\/WASOG statement on sarcoidosis. 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