{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:07:14Z","timestamp":1787317634205,"version":"build-2736575974"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T00:00:00Z","timestamp":1576022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006364","name":"Institut National Du Cancer","doi-asserted-by":"publisher","award":["R01CA067262"],"award-info":[{"award-number":["R01CA067262"]}],"id":[{"id":"10.13039\/501100006364","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006364","name":"Institut National Du Cancer","doi-asserted-by":"publisher","award":["UM1CA17626"],"award-info":[{"award-number":["UM1CA17626"]}],"id":[{"id":"10.13039\/501100006364","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000125","name":"National Institute for Occupational Safety and Health","doi-asserted-by":"publisher","award":["2015\u2010M\u201061780"],"award-info":[{"award-number":["2015\u2010M\u201061780"]}],"id":[{"id":"10.13039\/100000125","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000125","name":"National Institute for Occupational Safety and Health","doi-asserted-by":"publisher","award":["OH009803"],"award-info":[{"award-number":["OH009803"]}],"id":[{"id":"10.13039\/100000125","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Night shift work is associated with cardiovascular disease, but its associations with cardiovascular disease biomarkers are unclear. We investigated these associations in a study of female nurses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We used data from the Nurses\u2019 Health Study II for total cholesterol, low\u2010density lipoprotein cholesterol, high\u2010density lipoprotein (HDL) cholesterol, triglycerides, C\u2010reactive protein (CRP), and fibrinogen. The sample sizes for our analysis ranged from 458 (fibrinogen) to 3574 (total cholesterol). From questionnaires, we determined the number of night shifts worked in the 2 weeks before blood collection and total years of rotating night shift work. We used quantile regression to estimate differences in biomarker levels by shift work history, adjusting for potential confounders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Nurses working 1 to 4 recent night shifts had median HDL cholesterol levels 4.4\u2009mg\/dL (95% confidence interval [CI]: 0.3, 7.5) lower than nurses without recent night shifts. However, working \u22655 recent night shifts and years of rotating night shift work were not associated with HDL cholesterol. There was no association between recent night shifts and CRP, but median CRP levels were 0.1 (95% CI: 0.0, 0.2), 0.2 (95% CI: 0.1, 0.4), and 0.2 (95% CI: 0.0, 0.4)\u2009mg\/L higher among nurses working rotating night shifts for 1 to 5, 6 to 9, and \u226510 years compared with nurses never working rotating night shifts. These associations were attenuated when excluding postmenopausal women and women taking statins. We observed no associations between night shift work and other biomarkers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We found suggestive evidence of adverse short\u2010term and long\u2010term effects of night shift work on select cardiovascular disease biomarkers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ajim.23079","type":"journal-article","created":{"date-parts":[[2019,12,12]],"date-time":"2019-12-12T00:14:48Z","timestamp":1576109688000},"page":"240-248","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Night shift work and cardiovascular disease biomarkers in female nurses"],"prefix":"10.1002","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2544-3110","authenticated-orcid":false,"given":"Candice Y.","family":"Johnson","sequence":"first","affiliation":[{"name":"National Institute for Occupational Safety and Health Centers for Disease Control and Prevention  Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren J.","family":"Tanz","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health  Boston Massachusetts"},{"name":"Division of Women's Health Brigham and Women's Hospital  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina C.","family":"Lawson","sequence":"additional","affiliation":[{"name":"National Institute for Occupational Safety and Health Centers for Disease Control and Prevention  Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4337-9415","authenticated-orcid":false,"given":"Eva S.","family":"Schernhammer","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health  Boston Massachusetts"},{"name":"Channing Division of Network Medicine, Department of Medicine Brigham and Women's Hospital and Harvard Medical School  Boston Massachusetts"},{"name":"Department of Epidemiology Center for Public Health, Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3752-1067","authenticated-orcid":false,"given":"C\u00e9line","family":"Vetter","sequence":"additional","affiliation":[{"name":"Department of Integrative Physiology University of Colorado Boulder Boulder Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5066-8808","authenticated-orcid":false,"given":"Janet W.","family":"Rich\u2010Edwards","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health  Boston Massachusetts"},{"name":"Division of Women's Health Brigham and Women's Hospital  Boston Massachusetts"},{"name":"Channing Division of Network Medicine, Department of Medicine Brigham and Women's Hospital and Harvard Medical School  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,11]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.4454"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.3700"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.3727"},{"key":"e_1_2_11_5_1","volume-title":"Working time around the world: trends in working hours, laws and policies in a global comparative perspective","author":"Lee S","year":"2007"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1516953113"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0808180106"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.07.050"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004589"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0748730417697537"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40557-016-0135-y"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)01376-8"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.27.6.1318"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2008.867"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/32.2.200"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2011.09.004"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwm348"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000052939.59093.45"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1257\/jep.15.4.143"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.1330"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2017.78"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2015.11.013"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-010-9438-4"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-015-2345-8"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.3109\/07420528.2011.580869"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.1.64"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/13697130601114917"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-198310000-00004"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.594"}],"container-title":["American Journal of Industrial Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajim.23079","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajim.23079","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ajim.23079","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajim.23079","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T15:06:37Z","timestamp":1694099197000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajim.23079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,11]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1002\/ajim.23079"],"URL":"https:\/\/doi.org\/10.1002\/ajim.23079","archive":["Portico"],"relation":{},"ISSN":["0271-3586","1097-0274"],"issn-type":[{"value":"0271-3586","type":"print"},{"value":"1097-0274","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,11]]},"assertion":[{"value":"2019-09-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}