{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T18:50:53Z","timestamp":1787856653681,"version":"build-2784847793"},"reference-count":28,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T00:00:00Z","timestamp":1720051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To update and extend the examination of cancer incidence in a cohort of Danish firefighters, now adding 7 years of follow\u2010up and 2766 additional firefighters. The primary focus was directed toward cancer sites that recently contributed to the hazard evaluation conducted by the International Agency for Research on Cancer (IARC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The updated cohort consisted of 11,827 male Danish firefighters who were followed up for cancer from 1968 to 2021. Cohort cancer morbidity was compared with a working population reference group, and standardized incidence ratios (SIR) were used for estimation of relative risks, along with 95% confidence intervals (95% CI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among full\u2010time firefighters, SIR of skin melanoma was 1.30 (95% CI: 1.02\u20131.66), and SIR\u2009=\u20091.37 (95% CI: 1.02\u20131.85) for over 5 years of employment. Slightly positive associations were also observed for cancer of the urinary bladder (SIR\u2009=\u20091.16; 95% CI: 0.93\u20131.45), prostate (SIR\u2009=\u20091.11; 95% CI: 0.97\u20131.28), and testis (SIR\u2009=\u20091.11; 95% CI: 0.75\u20131.63).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This updated study provides evidence indicating an elevated risk of skin melanoma in firefighters. Consistent with IARC's evaluation, we also identified positive associations for urinary bladder, prostate, and testis cancer. In contrast, our findings did not suggest an increased risk of colon cancer, non\u2010Hodgkin lymphoma, and mesothelioma. The latter may be due to small numbers in our still relatively young cohort. Continuous follow\u2010up for cancer in firefighters is warranted, including assessment of influence from surveillance bias.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.23635","type":"journal-article","created":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T05:49:28Z","timestamp":1720158568000},"page":"857-864","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Cancer incidence in a cohort of Danish firefighters: An extended long\u2010term follow\u2010up 1968\u20132021"],"prefix":"10.1002","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5158-696X","authenticated-orcid":false,"given":"Julie E.","family":"Pedersen","sequence":"first","affiliation":[{"name":"Danish Cancer Institute, Danish Cancer Society Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kajsa U.","family":"Petersen","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine Copenhagen University Hospital \u2010 Bispebjerg and Frederiksberg Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria\u2010Helena G.","family":"Andersen","sequence":"additional","affiliation":[{"name":"National Research Centre for the Working Environment Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne T.","family":"Saber","sequence":"additional","affiliation":[{"name":"National Research Centre for the Working Environment Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulla","family":"Vogel","sequence":"additional","affiliation":[{"name":"National Research Centre for the Working Environment Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niels E.","family":"Ebbeh\u00f8j","sequence":"additional","affiliation":[{"name":"Department of Occupational Health and Social Medicine Holb\u00e6k Hospital Holb\u00e6k Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina K.","family":"Jensen","sequence":"additional","affiliation":[{"name":"Clinical Pharmacology, Pharmacy and Environmental Medicine University of Southern Denmark Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regitze S.","family":"Wils","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine Copenhagen University Hospital \u2010 Bispebjerg and Frederiksberg Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens P.","family":"Bonde","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine Copenhagen University Hospital \u2010 Bispebjerg and Frederiksberg Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnni","family":"Hansen","sequence":"additional","affiliation":[{"name":"Danish Cancer Institute, Danish Cancer Society Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,4]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"Occupational Exposure as a Firefighter. 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