{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T03:24:54Z","timestamp":1782703494464,"version":"3.54.5"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T00:00:00Z","timestamp":1743552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000125","name":"National Institute for Occupational Safety and Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000125","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>People participating in the rescue, recovery, and clean\u2010up effort after the September 11, 2001 attack on the World Trade Center (WTC) were exposed to a complex mix of noxious substances and subsequently experienced elevated gastroesophageal reflux disease (GERD) incidence, the second\u2010most\u2010common WTC\u2010related condition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Longitudinal WTC Health Program data, collected between July 2002 and December 2022, were used to describe the sample characteristics, diagnostic procedures, and treatment of consenting cohort members with self\u2010reported GERD who reported incident GERD for a year or longer (<jats:italic>n<\/jats:italic>\u2009=\u200919,067). Cross\u2010tabulations and binomial logistic regression, adjusted for confounders including comorbidities, assessed the associations with intermittent and resolved, compared with unresolved, GERD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>12.6% of the study cohort reported intermittent GERD; 5.5% reported GERD resolution. Analyses indicated that most GERD resolution was reported by people of color and those with body mass index &lt;25, and by cohort members who had longer postdiagnosis follow\u2010up and implemented dietary modifications together with proton pump inhibitors or Program\u2010approved antacids. GERD\u2010certified members who underwent endoscopy, used medications without dietary modifications, or used bed head\u2010elevation, and those with Barrett's disease (5.8%) or esophageal cancer (0.1%) may have had more severe GERD and reported little resolution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The use of GERD services was consistent with clinical guidelines. Members' implementing dietary modifications in conjunction with proton pump inhibitors or Program\u2010approved antacids reported more resolution and may have had less severe GERD. Earlier diagnosis and intervention might increase earlier therapeutic resolution.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.23721","type":"journal-article","created":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T16:46:37Z","timestamp":1743785197000},"page":"473-483","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Gastroesophageal Reflux Disease in the World Trade Center Health Program General Responder Cohort"],"prefix":"10.1002","volume":"68","author":[{"given":"Christopher R.","family":"Dasaro","sequence":"first","affiliation":[{"name":"Department of Environmental Medicine, World Trade Center Health Program General Responder Data Center Icahn School of Medicine at Mount Sinai New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Sabra","sequence":"additional","affiliation":[{"name":"Department of Environmental Medicine, World Trade Center Health Program General Responder Data Center Icahn School of Medicine at Mount Sinai New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry S.","family":"Sacks","sequence":"additional","affiliation":[{"name":"Department of Environmental Medicine, World Trade Center Health Program General Responder Data Center Icahn School of Medicine at Mount Sinai New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin J.","family":"Luft","sequence":"additional","affiliation":[{"name":"Department of Medicine, World Trade Center Health Program Clinical Center of Excellence Stony Brook University Medical Center Stony Brook NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise J.","family":"Harrison","sequence":"additional","affiliation":[{"name":"World Trade Center Health Program Clinical Center of Excellence, NYU Langone Medical Center New York University School of Medicine New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris G.","family":"Udasin","sequence":"additional","affiliation":[{"name":"World Trade Center Health Program Clinical Center of Excellence, Environmental and Occupational Health Sciences Institute Rutgers University Biomedical Sciences Piscataway NJ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Crane","sequence":"additional","affiliation":[{"name":"World Trade Center Health Program Clinical Center of Excellence, Department of Environmental Medicine Icahn School of Medicine at Mount Sinai New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline M.","family":"Moline","sequence":"additional","affiliation":[{"name":"Department of Occupational Medicine, Epidemiology and Prevention, World Trade Center Health Program Clinical Center of Excellence Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell Hempstead NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Winston","family":"Kwa","sequence":"additional","affiliation":[{"name":"Department of Environmental Medicine, World Trade Center Health Program General Responder Data Center Icahn School of Medicine at Mount Sinai New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew C.","family":"Todd","sequence":"additional","affiliation":[{"name":"Department of Environmental Medicine, World Trade Center Health Program General Responder Data Center Icahn School of Medicine at Mount Sinai New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3381-7602","authenticated-orcid":false,"given":"Nancy L.","family":"Sloan","sequence":"additional","affiliation":[{"name":"Department of Environmental Medicine, World Trade Center Health Program General Responder Data Center Icahn School of Medicine at Mount Sinai New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan L.","family":"Teitelbaum","sequence":"additional","affiliation":[{"name":"Department of Environmental Medicine, World Trade Center Health Program General Responder Data Center Icahn School of Medicine at Mount Sinai New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,2]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2006.05.127"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.explore.2006.06.008"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.02110703"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12940-019-0449-7"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61180-X"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.22634"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-304269"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.0800291"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000001538"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/19338244.2023.2171958"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2009.200063"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.670"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.4292\/wjgpt.v5.i3.105"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.9.965"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2020.7238"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2015.04.176"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2019.06.42"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002095.pub5"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11185268"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9865963"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-021-08386-1"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-019-04218-3"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17197290"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyv099"},{"key":"e_1_2_11_26_1","unstructured":"J H. Policy and Procedures for Certification of Physician Determinations for Aerodigestive and Cancer Health Conditions. Centers for Disease Control and Prevention. Updated 2018 accessed October 8 2024 https:\/\/www.cdc.gov\/wtc\/pdfs\/policies\/wtchpppcertphysdetfinal20feb2015-508.pdf."},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.07.049"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000000854"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/biom.13249"},{"issue":"6","key":"e_1_2_11_30_1","first-page":"411","article-title":"GERD in Minority Populations","volume":"7","author":"Friedenberg F. K.","year":"2011","journal-title":"Gastroenterology & Hepatology"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.03.077"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00849.x"},{"issue":"360","key":"e_1_2_11_33_1","first-page":"1","article-title":"Prevalence of Obesity and Severe Obesity Among Adults: United States, 2017\u20132018","author":"Hales C. M.","year":"2020","journal-title":"NCHS Data Brief"}],"container-title":["American Journal of Industrial Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajim.23721","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T04:03:16Z","timestamp":1744257796000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajim.23721"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,2]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1002\/ajim.23721"],"URL":"https:\/\/doi.org\/10.1002\/ajim.23721","archive":["Portico"],"relation":{},"ISSN":["0271-3586","1097-0274"],"issn-type":[{"value":"0271-3586","type":"print"},{"value":"1097-0274","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,2]]},"assertion":[{"value":"2024-10-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}