{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T05:40:03Z","timestamp":1697866803609},"reference-count":13,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2007,1,19]],"date-time":"2007-01-19T00:00:00Z","timestamp":1169164800000},"content-version":"vor","delay-in-days":8419,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[1984,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study is a component of a long\u2010term, follow\u2010up study aimed at evaluation of immunological and neurological findings with regard to the early detection of malignancies among patients at high risk of developing cancer.<\/jats:p><jats:p>One hundred fifteen patients with diagnosed asbestosis were examined neurologically and immunologically (rheumatoid factor, antinuclear antibodies, C3 and C4 and circulating immune complexes). Patients with nervous system involvement (63 cases; 55%) revealed no significant immunological differences when compared with the other patients except for a more common presence of antinuclear antibodies among patients without nervous system involvement (21% vs 6%, p &lt; 0.05). Significantly increased Wa\u2010Ro titers (&gt; 1\/128) were found for 3\u20134% of the patients whose asbestosis was either progressive or not as to radiological fibrosis, whereas only 0.4% of the blood donors had a significantly increased Wa\u2010Ro titer. The respective figures of latex agglutination (&gt; 1\/32) were found for 14\u201319% of the asbestosis patients whereas in 0.8% of the blood donors. The mean level of C3 was higher among progressive than nonprogressive asbestosis cases (1.48 vs 1.34, p &lt; 0.05). Patients with radiographic progression of asbestosis had higher IgG\u2010antinuclear antibody titers than the patients without progression.<\/jats:p>","DOI":"10.1002\/ajim.4700050605","type":"journal-article","created":{"date-parts":[[2007,4,15]],"date-time":"2007-04-15T21:48:31Z","timestamp":1176673711000},"page":"461-469","source":"Crossref","is-referenced-by-count":3,"title":["Immunological aspects of asbestosis: Patients' neurological signs and asbestosis progression"],"prefix":"10.1002","volume":"5","author":[{"given":"Matti S.","family":"Huuskonen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorma A.","family":"R\u00e4s\u00e4nen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juhani","family":"Juntunen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timo","family":"Partanen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,19]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1979.tb18715.x"},{"key":"e_1_2_1_3_1","unstructured":"HuuskonenMS. (1979): \u201cAsbestosis in Finland.\u201d Academic Dissertation Medical Faculty of the University of Helsinki Helsinki."},{"key":"e_1_2_1_4_1","first-page":"3","volume-title":"Neurobehavioral Methods. Advances in Biosciences","author":"Juntunen J","year":"1983"},{"key":"e_1_2_1_5_1","first-page":"59","volume-title":"Occupational Neurology","author":"Juntunen J","year":"1982"},{"key":"e_1_2_1_6_1","first-page":"228","article-title":"Tumor markers and neurological signs in asbestosis","volume":"90","author":"Juntunen J","year":"1982","journal-title":"Acta Neurol Scand"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0013-9351(80)90128-0"},{"key":"e_1_2_1_8_1","first-page":"1301","volume-title":"Peripheral Neuropathy","author":"McLeod JG","year":"1975"},{"key":"e_1_2_1_9_1","volume-title":"Asbestos and Disease","author":"Selikoff IJ","year":"1978"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700030109"},{"key":"e_1_2_1_11_1","volume-title":"Immunology of the Lung","author":"Turner\u2010Warwick M","year":"1978"},{"key":"e_1_2_1_12_1","first-page":"168","article-title":"Immunological diagnosis of rheumatoid arthritis and systemic lupus erythematosus","volume":"7","author":"Wager O","year":"1975","journal-title":"Ann Clin Res"},{"key":"e_1_2_1_13_1","volume-title":"Kliininen Immunologinen Laboratorio: Ohjekirja","author":"Wager O","year":"1982"},{"key":"e_1_2_1_14_1","first-page":"149","article-title":"Evaluation of six tests for circulating IgG complexes with special reference to IgM rheumatoid factors: Analysis of systemic lupus erythematosus and rheumatoid arthritis series","volume":"46","author":"Wager O","year":"1981","journal-title":"Clin Exp Immunol"}],"container-title":["American Journal of Industrial Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajim.4700050605","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajim.4700050605","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T15:37:26Z","timestamp":1697816246000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajim.4700050605"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,1]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1984,1]]}},"alternative-id":["10.1002\/ajim.4700050605"],"URL":"https:\/\/doi.org\/10.1002\/ajim.4700050605","archive":["Portico"],"relation":{},"ISSN":["0271-3586","1097-0274"],"issn-type":[{"value":"0271-3586","type":"print"},{"value":"1097-0274","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,1]]}}}