{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T09:32:13Z","timestamp":1777109533037,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,1,12]],"date-time":"2007-01-12T00:00:00Z","timestamp":1168560000000},"content-version":"vor","delay-in-days":7316,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[1987,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The value of measurements of zinc protoporphyrin in blood (ZPP) in the surveillance of workers occupationally exposed to lead has been studied. From a group of referents, consisting of 1,088 men and 511 women, it has been established that the normal mean ZPP is in the region of 25 \u03bcg\/100 ml, and only rarely do values exceed 45 \u03bcg\/100 ml. The higher ZPP values are frequently associated with low blood hemoglobin concentrations and appear to be manifestations of an iron\u2010deficiency anemia. Women have higher ZPP values than men; smoking has no influence. Measurements of ZPP and blood lead concentration (PbB) have been made every other month for 2.5 years on a group of around 200 men and 40 women exposed to lead in a storage battery factory. The mean ZPP of the group throughout the period was 70.9 \u03bcg\/100 ml blood, and a linear relation between log ZPP and PbB in the PbB range of 10\u201080 \u03bcg\/100 ml has been established. ZPP thresholds in the control of excessive occupational lead exposure, and the economic advantage of ZPP measurements over PbB, are discussed.<\/jats:p>","DOI":"10.1002\/ajim.4700120404","type":"journal-article","created":{"date-parts":[[2007,4,17]],"date-time":"2007-04-17T06:17:10Z","timestamp":1176790630000},"page":"385-398","source":"Crossref","is-referenced-by-count":14,"title":["Monitoring of zinc protoporphyrin levels in blood following occupational lead exposure"],"prefix":"10.1002","volume":"12","author":[{"given":"Karl","family":"Wildt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maths","family":"Berlin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per Erik","family":"Isberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,12]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00378056"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00378618"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00381417"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1093\/clinchem\/23.2.270","article-title":"The hematofluorimeter","volume":"23","author":"Blumberg WE","year":"1977","journal-title":"Clin Chem"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/000456328201900202"},{"key":"e_1_2_1_7_1","first-page":"897","article-title":"Zinc protoporphyrin in blood as a biological indicator of chrome lead intoxication","volume":"1","author":"Eisinger J","year":"1978","journal-title":"J Environ Pathol Toxicol"},{"key":"e_1_2_1_8_1","first-page":"28","article-title":"Reference values of erythrocytary zinc protoporphyrin in biological monitoring of occupational lead exposure","volume":"20","author":"Franco G","year":"1984","journal-title":"Quad Sclavo Diagn"},{"key":"e_1_2_1_9_1","first-page":"52","article-title":"Occupational lead exposure in Denmark: Screening with the haematofluorometer","volume":"36","author":"Grandjean P","year":"1979","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365517809102434"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/15298667991430163"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01274136"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/15298668191419334"},{"key":"e_1_2_1_14_1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1093\/clinchem\/21.1.93","article-title":"Zinc protoporphyrin (ZPP): A simple, sensitive, fluoreometric screenng test for lead poisoning","volume":"21","author":"Lamola A\u2010A","year":"1975","journal-title":"Clin Chem"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0013-9351(77)90037-8"},{"key":"e_1_2_1_16_1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1289\/ehp.782597","article-title":"Hemoglobin, serum iron, and zinc protoporphyrin in lead\u2010exposed workers","volume":"25","author":"Lillis R","year":"1978","journal-title":"Environ Health Perspect"},{"key":"e_1_2_1_17_1","first-page":"66","volume-title":"International Conference: Management and Control of Heavy Metals in the Environment","author":"Odone P","year":"1979"},{"key":"e_1_2_1_18_1","first-page":"932","article-title":"A micromethod for free erythrocyte porphyrins. The FEP test","volume":"81","author":"Piomelli S","year":"1973","journal-title":"J Lab Clin Med"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00539128"},{"key":"e_1_2_1_20_1","first-page":"527","article-title":"The influence of sex and of chelation therapy on erythrocyte protoporphyrin and urinary \u03b4\u2010aminolevulinic acid in lead\u2010exposed workers","volume":"21","author":"Roels HA","year":"1979","journal-title":"J Occup Med"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00538993"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0013-9351(81)90033-5"},{"key":"e_1_2_1_23_1","first-page":"120","article-title":"Subclinical effects of chronic increased lead absorption\u2014a prospective study","volume":"24","author":"Valentine JL","year":"1982","journal-title":"J Occup Med"}],"container-title":["American Journal of Industrial Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajim.4700120404","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajim.4700120404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T14:39:01Z","timestamp":1697899141000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajim.4700120404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,1]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1987,1]]}},"alternative-id":["10.1002\/ajim.4700120404"],"URL":"https:\/\/doi.org\/10.1002\/ajim.4700120404","archive":["Portico"],"relation":{},"ISSN":["0271-3586","1097-0274"],"issn-type":[{"value":"0271-3586","type":"print"},{"value":"1097-0274","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,1]]}}}