{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T08:52:27Z","timestamp":1759481547524},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,1,12]],"date-time":"2007-01-12T00:00:00Z","timestamp":1168560000000},"content-version":"vor","delay-in-days":7316,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[1987,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Nine workers at a 55\u2010gallon drum manufacturing plant had history of exposure to a paint powder that contained trimellitic anhydride (TMA). Environmental monitoring revealed airborne levels of TMA to be over 100 times the OSHA permissible exposure limit of 0.04 mg\/m<jats:sup>3<\/jats:sup>. The exposed workers were evaluated in a cross\u2010sectional study by questionnaire, physical examination, screening pulmonary function tests, serial peak expiratory flow rates (PEFR), and serum antibody levels. Four workers had symptoms consistent with TMA\u2010induced irritant effects. Three had symptoms and IgG levels consistent with TMA late respiratory systemic syndrome (LRSS). Two of these three had PEFR changes that showed significant drops (&gt;20%) 12\u201018 hours after the end of a work shift. The material safety data sheet for the paint powder failed to list TMA as an ingredient. Despite the well\u2010described toxic effects of TMA, the present study documents that TMA\u2010related illness may continue to be a problem in situations where workers and management are not properly notified of the potential hazards. The measurement of PEFR may be useful in identifying TMA\u2010exposed workers with LRSS.<\/jats:p>","DOI":"10.1002\/ajim.4700120406","type":"journal-article","created":{"date-parts":[[2007,4,17]],"date-time":"2007-04-17T08:17:29Z","timestamp":1176797849000},"page":"407-417","source":"Crossref","is-referenced-by-count":1,"title":["Trimellitic anhydride exposure in a 55\u2010gallon drum manufacturing plant: Clinical, immunologic, and industrial hygiene evaluation"],"prefix":"10.1002","volume":"12","author":[{"given":"Gideon","family":"Letz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee","family":"Wugofski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James E.","family":"Cone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roy","family":"Patterson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen E.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie C.","family":"Grammer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,12]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(82)80009-2"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(83)90634-6"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.34.3.308"},{"key":"e_1_2_1_5_1","unstructured":"California Manufacturers Association(1984): Sacramento Report (unpublished) p6."},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1984.tb02652.x"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.82.3.306"},{"key":"e_1_2_1_8_1","first-page":"691","volume-title":"Allergic Diseases, Diagnosis and Management","author":"Grammer LC","year":"1985"},{"key":"e_1_2_1_9_1","unstructured":"GrammerLC HarrisKE ChandlerMJ Flaherty D Patterson R: Establishing clinical and immunologic criteria for diagnosis of occupational immunologic lung disease with phthalic anhydride and tetrachlorophthalic anhydride exposures as a model (accepted for publ.)J Occ Med 1987."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.35.10.732"},{"key":"e_1_2_1_11_1","first-page":"1","article-title":"Allergic reactions to industrial chemicals","volume":"2","author":"McGrath KG","year":"1983","journal-title":"Clin Immunol Rev"},{"key":"e_1_2_1_12_1","first-page":"671","article-title":"Four\u2010year evaluation of workers exposed to trimellitic anhydride","volume":"26","author":"McGrath KG","year":"1984","journal-title":"J Occup Med"},{"key":"e_1_2_1_13_1","unstructured":"National Institute of Occupational Safety and Health(1978): \u201cCurrent Intelligence Bulletin 21\u2014Trimellitic Anhydride (TMA).\u201d DHEW (NIOSH) Pub No. 78\u2013121."},{"key":"e_1_2_1_14_1","unstructured":"NIOSH(1980)Manual of Analytic Methods 2nd ed Vol 6 Proceedures and Chemical Analytic Methods no. 322. 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