{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T19:08:19Z","timestamp":1780081699179,"version":"3.54.0"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,1,19]],"date-time":"2007-01-19T00:00:00Z","timestamp":1169164800000},"content-version":"vor","delay-in-days":6592,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[1989,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The role of asbestos in the etiology of lung cancer and of mesothelioma of the pleura and peritoneum has been well documented. The evidence for a causal association between asbestos and other human cancers is not as extensive but suggests that asbestos may be carcinogenic at several different sites. This paper is concerned specifically with a possible causal association between asbestos and human kidney cancer. A review of the evidence to date indicates that only three human studies have sufficient statistical power to detect an excess mortality from kidney cancer among workers exposed to asbestos. All three were occupational cohort studies, and two of these gave strong direct evidence for such an excess; a study of U.S. insulators (kidney cancer SMR = 2.22, 90% CI 1.44\u20133.30), and a study of U.S. asbestos products company workers (kidney cancer SMR = 2.76, 90% CI 1.29\u20135.18). The third study, of Italian shipyard workers, reported excess mortality from \u201ccancers of the kidney, urinary bladder, and other urinary organs\u201d (SMR = 1.98, 90% CI 1.42\u20132.70). Further support for a causal association includes studies finding asbestos fibers in human kidneys and urine, as well as reports of kidney tumors in two animal bioassays. It is concluded that asbestos should be regarded as a probable cause of human kidney cancer.<\/jats:p>","DOI":"10.1002\/ajim.4700160207","type":"journal-article","created":{"date-parts":[[2007,4,18]],"date-time":"2007-04-18T03:16:52Z","timestamp":1176866212000},"page":"159-166","source":"Crossref","is-referenced-by-count":32,"title":["Asbestos and kidney cancer: The evidence supports a causal association"],"prefix":"10.1002","volume":"16","author":[{"given":"Allan H.","family":"Smith","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie I.","family":"Shearn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rose","family":"Wood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,1,19]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.77.2.133"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113244"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.219478"},{"key":"e_1_2_1_5_1","first-page":"396","article-title":"Asbestos and cancer: A cohort followed up to death","volume":"44","author":"Enterline PE","year":"1987","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_6_1","first-page":"437","article-title":"Tierexperimentelle Untersuchungen uber eine kanzerogene Wirkung von Asbestfiltermaterial nach oraler Aufnahme","volume":"46","author":"Gibel W","year":"1976","journal-title":"Arch Geschwulst"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700030309"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1979.tb18749.x"},{"key":"e_1_2_1_9_1","volume-title":"IARC \u201cMonographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man: Asbestos","author":"International Agency for Research on Cancer","year":"1977"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-107-2-224"},{"key":"e_1_2_1_11_1","first-page":"11","article-title":"Dust exposure and mortality in chrysotile mining, 1910\u201375","volume":"37","author":"McDonald JC","year":"1980","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_12_1","first-page":"275","article-title":"Population based case\u2010control study of renal cell carcinoma","volume":"72","author":"McLaughlin JK","year":"1984","journal-title":"JNCI"},{"key":"e_1_2_1_13_1","volume-title":"Toxicology and carcinogenesis studies of chrysotile asbestos in F344\/N rats","author":"National Toxicology Program","year":"1985"},{"key":"e_1_2_1_14_1","first-page":"4","article-title":"Mortality of factory workers in East London 1933\u201380","volume":"42","author":"Newhouse ML","year":"1985","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01057574"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01059588"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1979.tb18738.x"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1979.tb18711.x"},{"key":"e_1_2_1_19_1","volume-title":"Smoking and Health: A report of the Surgeon General","author":"U.S. Department of Health, Education and Welfare","year":"1979"}],"container-title":["American Journal of Industrial Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajim.4700160207","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajim.4700160207","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T05:00:44Z","timestamp":1697950844000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajim.4700160207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,1]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1989,1]]}},"alternative-id":["10.1002\/ajim.4700160207"],"URL":"https:\/\/doi.org\/10.1002\/ajim.4700160207","archive":["Portico"],"relation":{},"ISSN":["0271-3586","1097-0274"],"issn-type":[{"value":"0271-3586","type":"print"},{"value":"1097-0274","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,1]]}}}