{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T13:53:05Z","timestamp":1758635585035},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,1,19]],"date-time":"2007-01-19T00:00:00Z","timestamp":1169164800000},"content-version":"vor","delay-in-days":6592,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[1989,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This retrospective analysis reviews the clinical experience of a major urban referral hospital with diffuse malignant pleural mesothelioma during the 14\u2010year period from 1973 through 1986. Seventy\u2010five cases of definite or equivocal mesothelioma were identified. There were four cases of primary malignant peritoneal mesothelioma, seven cases of benign fibrous mesothelioma, and 64 cases of diffuse malignant pleural mesothelioma. In 43 cases (67%) of diffuse malignant pleural mesothelioma, there was historic evidence of asbestos exposure. In 21 cases (33%), there was no known history of asbestos exposure. An increase in annual incidence of diffuse malignant pleural mesothelioma was observed over the study period, from three cases in 1973 to ten cases in 1986.<\/jats:p><jats:p>Despite greater awareness of this disease, the diagnosis remains a difficult one to establish given the nonspecific symptoms, signs and radiographic appearance, variable histologic appearance, and poor diagnostic sensitivity and specificity of thoracentesis and closed pleural biopsy. Thoracotomy, thoracoscopy, and CT\u2010guided needle biopsies gave higher yields and are the diagnostic measures of choice when diffuse malignant pleural mesothelioma is suspected.<\/jats:p>","DOI":"10.1002\/ajim.4700160405","type":"journal-article","created":{"date-parts":[[2007,4,18]],"date-time":"2007-04-18T08:54:10Z","timestamp":1176886450000},"page":"373-383","source":"Crossref","is-referenced-by-count":10,"title":["Diffuse malignant pleural mesothelioma in an urban hospital: Clinical spectrum and trend in incidence over time"],"prefix":"10.1002","volume":"16","author":[{"given":"Kenneth E.","family":"Shepherd","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. Christine","family":"Oliver","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Homayoun","family":"Kazemi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,19]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"335","article-title":"Chemotherapy in the treatment of malignant mesothelioma","volume":"8","author":"Aisner J","year":"1981","journal-title":"Semin Oncol"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1985.105"},{"key":"e_1_2_1_4_1","first-page":"313","article-title":"Clinical presentation and natural history of benign and malignant mesothelioma","volume":"8","author":"Antman KH","year":"1981","journal-title":"Semin Oncol"},{"key":"e_1_2_1_5_1","volume-title":"Asbestos\u2010Related Malignancy","author":"Antman K","year":"1987"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1984.tb132709.x"},{"key":"e_1_2_1_7_1","first-page":"187","article-title":"Asbestos\u2010related diseases of the lung and other organs: Their epidemiology and implications for clinical practice","volume":"114","author":"Becklake MR","year":"1976","journal-title":"Am Rev Respir Dis"},{"key":"e_1_2_1_8_1","first-page":"826","article-title":"Mesothelioma update for clinicians","volume":"134","author":"Becklake MR","year":"1986","journal-title":"Am Rev Respir Dis"},{"key":"e_1_2_1_9_1","first-page":"588","article-title":"Thoracoscopy in malignant pleural effusions","volume":"124","author":"Boutin C","year":"1981","journal-title":"Am Rev Respir Dis"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810601)47:11<2678::AID-CNCR2820471126>3.0.CO;2-9"},{"key":"e_1_2_1_11_1","first-page":"321","article-title":"The role of surgery in diffuse malignant mesothelioma of the pleura","volume":"8","author":"Butchart EG","year":"1981","journal-title":"Semin Oncol"},{"key":"e_1_2_1_12_1","first-page":"54","article-title":"Treatment of diffuse malignant mesothelioma\u2014a review","volume":"45","author":"Chahinian AP","year":"1978","journal-title":"Mt Sinai J Med (NY)"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-96-6-746"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1965.tb41141.x"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.3317.147"},{"key":"e_1_2_1_16_1","unstructured":"EPA Study of Asbestos\u2010Containing Materials in Public Buildings. A Report to Congress (1988): US Environmental Protection Agency Washington DC."},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.257.12.1569"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.40.1.19"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.95.3.590"},{"key":"e_1_2_1_20_1","first-page":"761","article-title":"The significance of asbestos exposure in the diagnosis of mesothelioma: A 28\u2010year experience from a major urban hospital","volume":"115","author":"Hasan FM","year":"1977","journal-title":"Am Rev Respir Dis"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(78)90853-7"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0007-0971(83)90068-2"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700030407"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.90.5.638"},{"key":"e_1_2_1_25_1","first-page":"207","article-title":"Histochemistry in the diagnosis of malignant mesothelioma","volume":"3","author":"Kannerstein M","year":"1973","journal-title":"Ann Clin Lab Sci"},{"key":"e_1_2_1_26_1","first-page":"497","article-title":"Malignant mesotheliomas: Improved differential diagnosis from lung adenocarcinomas using monoclonal antibodies 44\u20133A6 and 624A12","volume":"123","author":"Lee I","year":"1986","journal-title":"Am J Pathol"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1965.tb41140.x"},{"key":"e_1_2_1_28_1","first-page":"261","article-title":"Mesothelioma of pleura and peritoneum following exposure to asbestos in the London area","volume":"22","author":"Newhouse ML","year":"1965","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700030305"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7071597"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197902)43:2<627::AID-CNCR2820430233>3.0.CO;2-8"},{"key":"e_1_2_1_32_1","first-page":"461","article-title":"A population\u2010based case\u2010control study of mesothelioma deaths among US railroad workers","volume":"134","author":"Schenker MB","year":"1986","journal-title":"Am Rev Respir Dis"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1979.tb18711.x"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1979.tb18732.x"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700090502"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197603000-00004"},{"key":"e_1_2_1_37_1","first-page":"260","article-title":"Diffuse pleural mesothelioma and asbestos exposure in North Western Cape Province","volume":"17","author":"Wagner J","year":"1960","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_38_1","first-page":"409","article-title":"Projections of asbestos\u2010related disease 1980\u20132009","volume":"25","author":"Walker AM","year":"1983","journal-title":"J Occup Med"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198206000-00003"}],"container-title":["American Journal of Industrial Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajim.4700160405","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajim.4700160405","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T05:04:35Z","timestamp":1697951075000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajim.4700160405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,1]]},"references-count":38,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1989,1]]}},"alternative-id":["10.1002\/ajim.4700160405"],"URL":"https:\/\/doi.org\/10.1002\/ajim.4700160405","archive":["Portico"],"relation":{},"ISSN":["0271-3586","1097-0274"],"issn-type":[{"value":"0271-3586","type":"print"},{"value":"1097-0274","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,1]]}}}