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Not only had six genetically unrelated children been diagnosed with a primary intracranial tumor in a recent 2.4 year period in a rural county in Ohio, but each child had one parent employed by the same company (two mothers, four fathers). This represents an observed\/expected ratio &gt; 70 (p &lt; 0.001). All tumors were microscopically confirmed, and all case parents worked at the facility in question for at least 1 year prior to conception, during the index pregnancy, and for at least 6 months after birth. The place of parental employment was an electronics firm (Standard Industrial Classification [SIC] group number 367, electronic components and accessories), where more than 100 chemical compounds are used by the company in a manufacturing process. Results of the cluster investigation are described, including a description of the case series. This cancer cluster is unique in that the index case series is composed of the offspring of workers, not the workers themselves.<\/jats:p>","DOI":"10.1002\/ajim.4700190509","type":"journal-article","created":{"date-parts":[[2007,4,18]],"date-time":"2007-04-18T23:22:58Z","timestamp":1176938578000},"page":"643-653","source":"Crossref","is-referenced-by-count":17,"title":["Parental occupation and intracranial neoplasms of childhood: Anecdotal evidence from a unique occupational cancer cluster"],"prefix":"10.1002","volume":"19","author":[{"suffix":"III","given":"J. 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