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The cases were divided into four groups (22 lungs of persons exposed to ambient environmental pollution, 32 cases of mesothelioma, 38 cases of primary lung cancer, and 34 asbestosis cases, 13 of these with additional pleural plaques). Fibers were counted, measured, and mineralogically identified using a combination of X\u2010ray microanalysis and electron diffraction of the non\u2010oriented fiber. Concentration of fibrous particles (defined as particles above 1 \u03bcm in length with roughly parallel long sides and an aspect ratio of 5:1 and greater) was calculated as fibers 10<jats:sup>6<\/jats:sup>\/g dry lung weight. The concentration of chrysotile was found to be similar throughout the groups except for two cases in the asbestosis group with comparably high numbers of chrysotile. However, a remarkable difference for amphiboles could be observed between the groups. Asbestos bodies were mostly found in the asbestosis group. There was a rather good correlation between numbers of amphibole fibers and asbestos bodies, with an average ratio of 10:1. For compariso purposes between occupationally exposed\/non\u2010exposed individuals, a transition was found in the concentration range of 3\u201310<jats:sup>7<\/jats:sup> asbestos fibers\/g dried lung weight. \u00a9 1992 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajim.4700220105","type":"journal-article","created":{"date-parts":[[2007,4,19]],"date-time":"2007-04-19T18:18:10Z","timestamp":1177006690000},"page":"49-58","source":"Crossref","is-referenced-by-count":18,"title":["Electron microscopy analysis of mineral fibers in human lung tissue"],"prefix":"10.1002","volume":"22","author":[{"given":"Karl Heinz","family":"Friedrichs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Brockmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margit","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Wick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,1,19]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.26.3.224"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/00039896.1988.9935849"},{"key":"e_1_2_1_4_1","first-page":"310","article-title":"Alveolar and lung fibre levels in non\u2010occupationally exposed subjects","volume":"90","author":"Chiappino G","year":"1989","journal-title":"IARC Sci Publ"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(82)80227-X"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1980.122.5.669"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/01902148909062860"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1520\/STP39137S"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.41.3.167"},{"key":"e_1_2_1_10_1","first-page":"1","article-title":"Zur Dignit\u00e4t von Asbestk\u00f6rperchen\u2010Z\u00e4hlungen im Lungengewebe","volume":"19","author":"Eitner F","year":"1984","journal-title":"Arbeitsmed Sozialmed Pr\u00e4ventivmed"},{"key":"e_1_2_1_11_1","unstructured":"Fischer M.Brockmann M FriedrichsKH(1990):Tremolit\u2010assoziiertes Pleuramesotheliom.\u2010 Versicherungs\u2010medizinische Bewertung. 26. 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