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The individual time\u2010weighted toluene levels in air were 36 (median; range 8\u2013111) ppm. The printers' median toluene levels in blood were 1.7 (1.0\u20136.6) \u03bcmol\/1, and in subcutaneous adipose tissue 5.7 (2.5\u201321) mg\/kg fat. There was a negative association between blood toluene and plasma levels of prolactin. In eight printers, the levels of FSH and LH increased during a 4 week vacation, while the levels of thyroid stimulating hormone, free triiodothyronine, and free thyroxine decreased during the same period. The results indicate a slight, reversible efect of toluene on the cortical level or on the hypothalamic\u2010pituitary axis at exposures well below the permissible levels, possibly mediated through an effect on catecholamine neurotransmission. \u00a9 1992 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajim.4700220109","type":"journal-article","created":{"date-parts":[[2007,4,19]],"date-time":"2007-04-19T18:20:05Z","timestamp":1177006805000},"page":"99-107","source":"Crossref","is-referenced-by-count":27,"title":["Hormone status in occupational toluene exposure"],"prefix":"10.1002","volume":"22","author":[{"given":"B.\u2010G.","family":"Svensson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Nise","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.\u2010M.","family":"Erfurth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Nilsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Skerfving","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,1,19]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000124699"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(81)90340-9"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(81)90510-0"},{"key":"e_1_2_1_5_1","first-page":"43","article-title":"Increased amine turnover in several hypothalamic noradrenaline nerve terminal systems and changes in prolactin secretion in the male rat by exposure to various concentrations of toluene","volume":"4","author":"Andersson K","year":"1983","journal-title":"Neurotoxicology"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(84)90235-0"},{"key":"e_1_2_1_7_1","first-page":"826","article-title":"Impaired dopaminergic modulation of pituitary secretion in workers occupationally exposed to styrene: Further evidence from PRL response to TRH stimulation","volume":"29","author":"Arfini G","year":"1987","journal-title":"J Occup Med"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700080306"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-59-5-955"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-99-3-651"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365518509155244"},{"key":"e_1_2_1_12_1","first-page":"47","volume-title":"Frontiers in Neuroendocrinology","author":"Fuxe K","year":"1969"},{"key":"e_1_2_1_13_1","first-page":"249","volume-title":"Developments in Occupational Medicine","author":"Hogstedt C","year":"1981"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1159\/000122042"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-51-2-209"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-43-3-668"},{"key":"e_1_2_1_17_1","first-page":"721","article-title":"Toxicity of metabolites to dopaminergic systems and the behavioural effects of organic solvents (Editorial)","volume":"44","author":"Mutti A","year":"1987","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.2340"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00316123"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00409376"},{"key":"e_1_2_1_21_1","first-page":"407","article-title":"Elimination of toluene from venous blood and adipose tissue after occupational exposure","volume":"46","author":"Nise G","year":"1989","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/15298668691390386"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-86-5-988"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700040110"},{"key":"e_1_2_1_25_1","first-page":"372","article-title":"Deaths and tumours among rotogravure printers exposed to toluene","volume":"47","author":"Svensson B\u2010G","year":"1990","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_26_1","unstructured":"Svensson B\u2010G Nise G ErfurthEM Olsson H. 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