{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T21:52:35Z","timestamp":1767649955957},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2007,1,19]],"date-time":"2007-01-19T00:00:00Z","timestamp":1169164800000},"content-version":"vor","delay-in-days":4827,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[1993,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Psychometric testing is a key issue in neuropsychological toxicology assessment. Evaluation of methods for assessing general intellectual impairment is necessary as conventional neurology has been shown to be insensitive to the neurotoxic effects of solvents and metals. This study presents an analysis of a psychometric test battery from an investigation of psycho\u2010organic syndrome in a historical cohort of 96 metal degreasers with long\u2010term exposure to solvents, particularly trichloroethylene.<\/jats:p><jats:p>The neuropsychological test battery was a combination of Wechsler Adult Intelligence Scale (WAIS), Luria, and tests developed in Scandinavia. Linear regression analysis showed a significant dose\u2010response relation between increasing cumulative solvent exposure and impaired psychometric test performance in 9 out of 15 tests. Multivariate analysis, however, suggests that much of the variance was due to confounding variables, especially age, and to a lesser degree, primary intellectual function and word blindness. After control for confounding factors the strongest association with solvent exposure occurred for the following three tests: acoustic\u2010motor function, Paced Auditory Serial Addition Test (PASAT), and the visual gestalt test. \u00a9 1993 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajim.4700240506","type":"journal-article","created":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T15:29:30Z","timestamp":1177082970000},"page":"553-565","source":"Crossref","is-referenced-by-count":11,"title":["Psychometric tests for assessment of brain function after solvent exposure"],"prefix":"10.1002","volume":"24","author":[{"given":"Kurt","family":"Rasmussen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans Jeppe","family":"Jeppesen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svend","family":"Sabroe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,19]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-9450.1976.tb00231.x"},{"key":"e_1_2_1_3_1","first-page":"359","article-title":"Neurobehavioral tests used in NIOSH\u2010supported worksite studies 1973\u20131983","volume":"7","author":"Anger WK","year":"1985","journal-title":"Neurotoxicol Teratol"},{"key":"e_1_2_1_4_1","unstructured":"Arlien\u2010S\u00f8borg P(1991): Organic solvents and the nervous system. Report on a conference sponsored by the Commission of the European Communities and the Danish Ministry of Environment. Luxembourg: The Commission of the European Communities. Directorate\u2010General for Employment Social Affairs and Education."},{"key":"e_1_2_1_5_1","first-page":"125","article-title":"Monitoring neurotoxins in industry: Development of a neurobehavioral test battery","volume":"25","author":"Baker EL","year":"1983","journal-title":"J Occup Med"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00043764-198610000-00017"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700190605"},{"key":"e_1_2_1_8_1","volume-title":"Extended Manual of Neuropsychological Testing (in Danish)","author":"Bruun P","year":"1980"},{"key":"e_1_2_1_9_1","volume-title":"Luria's Neuropsychological Investigation","author":"Christensen AL","year":"1979"},{"key":"e_1_2_1_10_1","first-page":"292","article-title":"Neurobehavioral effects of occupational exposure to organic solvents among construction painters","volume":"44","author":"Fidler A","year":"1987","journal-title":"Br J Ind Med"},{"issue":"1","key":"e_1_2_1_11_1","first-page":"65","article-title":"Use of behavioral performance tests in the assessment of solvent toxicity","volume":"11","author":"Gamberale F","year":"1985","journal-title":"Scand J Work Environ Health"},{"key":"e_1_2_1_12_1","first-page":"374","article-title":"Psychological picture of manifest and latent carbon disulfide poisoning","volume":"28","author":"H\u00e4nninen H","year":"1971","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.2805"},{"key":"e_1_2_1_14_1","volume-title":"Behavioral Test Battery for Toxicopsychological Studies","author":"H\u00e4nninen H","year":"1979"},{"key":"e_1_2_1_15_1","volume-title":"Neuropsychological Toxicology. 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