{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T14:33:24Z","timestamp":1773239604773,"version":"3.50.1"},"reference-count":39,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,1,19]],"date-time":"2007-01-19T00:00:00Z","timestamp":1169164800000},"content-version":"vor","delay-in-days":4707,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[1994,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To evaluate chronic effects of acute organophosphate pesticide poisoning, quantitatively determined vibrotactile thresholds were measured as an index of peripheral neuropathy among agricultural workers in Nicaragua. Thirty\u2010six male workers were evaluated between 10 and 34 months after hospitalization for acute organophosphate poisoning and compared to an age\u2010 and sex\u2010matched community reference group. Vibrotactile thresholds were measured quantitatively in right and left index fingers and right and left great toes. Study subjects were stratified into three groups: 1) never poisoned; 2) poisoned with organophosphates other than methamidophos, agents which have not been reported to cause peripheral neuropathy; and 3) poisoned with methamidophos, a peripheral neurotoxin. For all digits, there was a statistically significant trend of increasing age\u2010and height\u2010adjusted thresholds across these three exposure categories. Over one fourth of patients previously poisoned with methamidophos we studied had abnormal vibrotactile thresholds. These results suggest that previously reported cases of organophosphate\u2010induced delayed polyneuropathy may represent only the worst disease in a spectrum of impairment, a sequela of exposure that may be much more common than previously thought. \u00a9 1994 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajim.4700250303","type":"journal-article","created":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T19:47:55Z","timestamp":1177098475000},"page":"325-334","source":"Crossref","is-referenced-by-count":58,"title":["Elevated quantitative vibrotactile threshold among workers previously poisoned with methamidophos and other organophosphate pesticides"],"prefix":"10.1002","volume":"25","author":[{"given":"Rob","family":"McConnell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Keifer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Rosenstock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,19]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1986.tb04637.x"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.4819.1068"},{"key":"e_1_2_1_4_1","first-page":"249","article-title":"Toxicological screening for organophosphorus\u2010induced delayed neurotoxicity: Complications in toxicity testing","volume":"9","author":"Cherniack M","year":"1988","journal-title":"Neurotoxicology"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj1770549"},{"key":"e_1_2_1_6_1","volume-title":"The Fruits of Crisis in Central America: Gambling on Non\u2010traditional Agriculture","author":"Conroy ME"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.10.4.432"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4757-1165-3_9"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneurpsyc.1942.02290100122010"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/00039896.1990.9936708"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1006\/enrs.1993.1023"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880141104"},{"key":"e_1_2_1_13_1","first-page":"635","article-title":"Reliability of a widely used test of peripheral cutaneous vibration sensitivity and a comparison of two testing protocols","volume":"45","author":"Gerr F","year":"1988","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_14_1","first-page":"181","volume-title":"New Developments in Electromyography and Clinical Neurophysiology","author":"Hern JEC","year":"1973"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00310333"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00690757"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1974.tb04404.x"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.3109\/10408447509079861"},{"issue":"1","key":"e_1_2_1_19_1","first-page":"176","article-title":"Dursban causes peripheral neuropathy","volume":"36","author":"Kaplan JG","year":"1986","journal-title":"Neurology"},{"key":"e_1_2_1_20_1","first-page":"39","article-title":"Jake paralysis","volume":"52","author":"Kidd JD","year":"1933","journal-title":"Bull Johns Hopkins Hospital"},{"key":"e_1_2_1_21_1","first-page":"465","article-title":"The pathogenesis of organophosphate poly neuropathy","volume":"21","author":"Lotti M","year":"1992","journal-title":"Toxicology"},{"key":"e_1_2_1_22_1","first-page":"517","article-title":"Occupational exposure to the cotton defoliants DEF and merphos","volume":"25","author":"Lotti M","year":"1983","journal-title":"J Occup Med"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00316329"},{"key":"e_1_2_1_24_1","first-page":"1","volume-title":"Recognition and Management of Pesticide Poisonings","author":"Morgan DP","year":"1989"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1978.00500320050011"},{"key":"e_1_2_1_26_1","volume-title":"SPSS\/PC+ V2.0 Base Manual for the IBM PC\/XT\/AT and PS\/2","author":"Norusis MJ","year":"1988"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90356-T"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/00039896.1988.9934372"},{"key":"e_1_2_1_29_1","first-page":"203","article-title":"Polyneuropathy following insecticide poisoning","volume":"232","author":"Senanayake N","year":"1985","journal-title":"J Neurol"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198201213060306"},{"key":"e_1_2_1_31_1","unstructured":"SetteWF(1991): Pesticide assessment guidelines subdivision F: Hazard evaluation\u2014human and domestic animals addendum 10\u2014Neurotoxicity series 81 82 and 83. 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