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This approach was needed because there are numerous chemical and physical agents and psychosocial stressors that may potentially impact the reproductive status of female office workers. Although video display terminals (VDTs) are typically the focus of spontaneous abortion (SAB) investigations, one cannot ignore other stressors in the environment. Magnetic field exposures within a payroll area were determined using a hand\u2010held survey meter and data logging dosimeter. On average, the full shift time\u2010weighted average exposures of workers to extremely low frequency (ELF) magnetic fields in the payroll office area ranged from 1.0 to 5.6 mG.<\/jats:p><jats:p>Influencing the investigation's protocol design were the Centers for Disease Control's (CDC's) recent Guidelines for Investigating Clusters of Health Events. Although these guidelines grew primarily out of cancer cluster investigations, we applied them in this instance and found them to be generalizable to reproductive hazards investigations. A spontaneous abortion excess was validated over a 2\u2010year period among 26 women with 32 reproductive events, with rates 1.5\u20132.5 times the expected, depending on comparison figures used. Lessons learned in the investigation, including the applicability of the CDC's Cluster Investigation Protocol and the enormous importance of risk perception and risk communication, are described. \u00a9 1994 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajim.4700250402","type":"journal-article","created":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T20:20:18Z","timestamp":1177100418000},"page":"463-475","source":"Crossref","is-referenced-by-count":8,"title":["Investigation of a spontaneous abortion cluster: Lessons learned"],"prefix":"10.1002","volume":"25","author":[{"given":"Melissa A.","family":"McDiarmid","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Breysse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter S. 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