{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:52:40Z","timestamp":1790895160664,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,1,19]],"date-time":"2007-01-19T00:00:00Z","timestamp":1169164800000},"content-version":"vor","delay-in-days":4158,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[1995,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cancers of the pleura, lung, and larynx between 1978 and 1989 among active male workers of Electricit\u00e9 de France\u2010Gaz de France were studied in association with asbestos exposure using a case\u2010control design nested within the cohort of workers of the company. The cohort included about 1,400,000 person\u2010years, corresponding to a mean of 117,000 men per year. Exposure to asbestos and to some potential occupational confounders selected among agents from groups I, IIa, and IIb of the International Agency for Research on Cancer was assessed by a job\u2010exposure matrix specific to the company. During the observation period, 12 cases of pleural cancer, 310 cases of lung cancer, and 116 cases of larynx cancer were registered in the cancer register of the company social security department. Four controls per case, matched for year of birth, were randomly selected among the cohort. Conditional logistic regression was used to estimate the odds ratios. A first analysis was conducted in order to assess the validity of the job\u2010exposure matrix by investigating already known relationships between asbestos exposure and asbestosis. For asbestosis, a strong exposure\u2010response relation was found with an odds ratio (OR) of 57.4 [95% confidence interval (CI): 17.0\u2013194.0] in the highest exposure group. There was an elevated risk of pleural cancer (OR, 4.8, CI, 1.2\u201319.8). For lung cancer, significant ORs of 2.0 (CI, 1.3\u20133.2) and 1.9 (CI, 1.2\u20133.0) were found among the two highest cumulative exposure groups; adjustement for confounders slightly decreased the ORs. Squamous cell neoplasm of the lung was associated with asbestos exposure. The association between larynx cancer and asbestos exposure showed a tendency towards a nonsignificant increase in ORs in the highest cumulative exposure categories; this tendency disappeared when adjusting for occupational confounders. This study showed that occupational exposure to asbestos could increase the risk of pleural and lung cancer in a sector in which exposure levels are not considered to be high compared with other industrial settings.<\/jats:p>","DOI":"10.1002\/ajim.4700280304","type":"journal-article","created":{"date-parts":[[2007,4,21]],"date-time":"2007-04-21T15:16:55Z","timestamp":1177168615000},"page":"339-352","source":"Crossref","is-referenced-by-count":34,"title":["Occupational respiratory cancer and exposure to asbestos: A case\u2010control study in a cohort of workers in the electricity and gas industry"],"prefix":"10.1002","volume":"28","author":[{"given":"E.","family":"Imbernon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Goldberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Bonenfant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Chevalier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Gu\u00e9nel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Vatr\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Dehaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,1,19]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700110102"},{"key":"e_1_2_1_3_1","first-page":"5","article-title":"Mortality in miners and millers of crocidolite in Western Australia","volume":"45","author":"Armstrong BK","year":"1988","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_4_1","first-page":"445","article-title":"Mortality from respiratory and digestive cancers among asbestos cement workers in Italy","volume":"15","author":"Botta M","year":"1991","journal-title":"Cancer Detect Prev"},{"issue":"2","key":"e_1_2_1_5_1","first-page":"565","article-title":"Studying the performance of a job exposure matrix","volume":"22","author":"Bouyer J","year":"1993","journal-title":"Int J Epidemiol"},{"key":"e_1_2_1_6_1","volume-title":"The Analysis of Case\u2010Control Studies. Statistical Methods in Cancer Research","author":"Breslow NE","year":"1980"},{"key":"e_1_2_1_7_1","first-page":"556","article-title":"A threshold for asbestos related lung cancer","volume":"43","author":"Browne K","year":"1986","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.2090"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"2984","DOI":"10.1001\/jama.1985.03350440062032","article-title":"Lung cancer cell type and asbestos exposure","volume":"253","author":"Churg A","year":"1985","journal-title":"JAMA"},{"key":"e_1_2_1_10_1","first-page":"412","article-title":"Smoking exposure to crocidolite, and the incidence of lung cancer and asbestosis","volume":"48","author":"De Klerk NH","year":"1991","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00121330"},{"key":"e_1_2_1_12_1","first-page":"81","article-title":"Mortality from lung cancer among asbestos workers","volume":"12","author":"Doll R","year":"1955","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_13_1","first-page":"396","article-title":"Asbestos and cancer: A cohort followed up to death","volume":"44","author":"Enterline PE","year":"1987","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a114294"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1979.tb18749.x"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1979.tb18714.x"},{"key":"e_1_2_1_17_1","first-page":"161","article-title":"Mortality of workers employed in two asbestos cement manufacturing plants","volume":"44","author":"Hughes JM","year":"1987","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000433-199009000-00012"},{"key":"e_1_2_1_19_1","first-page":"559","article-title":"MATEX: Une matrice emplois\u2010expostions destin\u00e9e \u00e0 la surveillance \u00e9pid\u00e9miologique des travailleurs d'une grande entreprise (EDF\u2010GDF)","volume":"52","author":"Imbernon E","year":"1991","journal-title":"Arch Mal Prof"},{"key":"e_1_2_1_20_1","volume-title":"Monographs on the Evaluation of the Carcinogenic Risk to Humans, Vols. 1\u201042 (Suppl. 7). Overall Evaluation of Carcinogenicity: An Updating of IARC Monographs","author":"International Agency for Research in Cancer (IARC)","year":"1987"},{"key":"e_1_2_1_21_1","volume-title":"Nomenclature des Professions et des Cat\u00e9gories Socio\u2010Professionnelles PCS","author":"Institut National de la Statistique et des Etudes Economiques (INSEE)","year":"1983"},{"key":"e_1_2_1_22_1","first-page":"43","article-title":"Estimated confounding from smoking in a cohort of 20,000 French electrical workers","volume":"50","author":"Lagorio S","year":"1992","journal-title":"Epidemiol Prev"},{"key":"e_1_2_1_23_1","first-page":"281","article-title":"Asbestos related health hazards among power plant workers","volume":"47","author":"Lerman Y","year":"1990","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_24_1","first-page":"65","volume-title":"Prevention of Respiratory Diseases","author":"McDonald JC","year":"1993"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.2307\/3431090"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.2307\/3431290"},{"key":"e_1_2_1_27_1","first-page":"3","volume-title":"Prevention of Respiratory Diseases","author":"Mur JM","year":"1993"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19920501)69:9<2244::AID-CNCR2820690906>3.0.CO;2-O"},{"key":"e_1_2_1_29_1","first-page":"615","article-title":"Individual asbestos exposure: Smoking and mortality. A cohort study in the asbestos cement industry","volume":"47","author":"Neuberger M","year":"1990","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_30_1","first-page":"810","article-title":"An update of cancer mortality among chysolite asbestos miners in Banlangero, northern Italy","volume":"47","author":"Piolatto G","year":"1990","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_31_1","first-page":"90","article-title":"Incidence of cancer and mortality among employees in the asbestos cement industry in Danemark","volume":"46","author":"Raffn E","year":"1989","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_32_1","first-page":"85","article-title":"Incidence of lung cancer by histological type among asbestos cement workers in Denmark","volume":"50","author":"Raffn E","year":"1993","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1991.tb24485.x"},{"key":"e_1_2_1_34_1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1183\/09031936.93.05030281","article-title":"The risk of lung cancer and mesothelioma after cessation of asbestos exposure: A prospective study of shipyard workers","volume":"5","author":"Sanden A","year":"1992","journal-title":"Eur Resp J"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19801215)46:12<2736::AID-CNCR2820461233>3.0.CO;2-L"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/00043764-198808000-00004"},{"key":"e_1_2_1_37_1","first-page":"298","article-title":"A study of the histological cell types of lung cancer in workers suffering from asbestosis in the United Kingdom","volume":"31","author":"Whitwell F","year":"1974","journal-title":"Br J Ind Med"}],"container-title":["American Journal of Industrial Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajim.4700280304","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajim.4700280304","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T16:21:36Z","timestamp":1698250896000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajim.4700280304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,9]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1995,9]]}},"alternative-id":["10.1002\/ajim.4700280304"],"URL":"https:\/\/doi.org\/10.1002\/ajim.4700280304","archive":["Portico"],"relation":{},"ISSN":["0271-3586","1097-0274"],"issn-type":[{"value":"0271-3586","type":"print"},{"value":"1097-0274","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,9]]}}}