{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T18:43:02Z","timestamp":1750963382328},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,1,19]],"date-time":"2007-01-19T00:00:00Z","timestamp":1169164800000},"content-version":"vor","delay-in-days":4128,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[1995,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Silicotics have increased mortality from tuberculosis (TB) and from nonmalignant respiratory diseases (NMRD), including silicosis and silicotuberculosis. Since the publication of the International Agency for Research on Cancer monograph in 1987 indicating that silica was a probable human carcinogen, there has been an extensive debate about the cancer risks among silicotics. The authors identified 590 claims for silicosis among a registry of lung diseases compiled from California Workers' Compensation cases from 1945 to 1975. Using state vital records, we determined the mortality risks from 1946 to 1991. Our findings confirmed that these claimants had a significantly elevated risk for all causes of death with a standardized mortality ratio (SMR) of 1.30 (95% confidence interval [CI] = 1.18, 1.43); TB had a SMR of 56.35 (95% CI = 41.10, 75.40) and NMRD a SMR of 3.80 (95% CI = 3.11, 4.60). Cancers of the trachea, bronchus, and lung had a SMR of 1.90 (95% CI = 1.35, 2.60). For malignancies of the large intestine, there was a previously unreported SMR of 2.08 (95% CI = 1.14, 3.50). Mortality from all diseases of the heart was significantly less than expected with a SMR of 0.68 (95% CI = 0.55, 0.83); cancers of the prostate and lymphatic system were also significantly low with SMRs of 0.26 (95% CI = 0.03, 0.94) and 0.17 (95% CI = 0.04, 0.97), respectively. Workers with silicosis should be warned about these chronic disease risks, and prevention efforts to control occupational silica dust exposure should become a higher priority.<\/jats:p>","DOI":"10.1002\/ajim.4700280403","type":"journal-article","created":{"date-parts":[[2007,4,21]],"date-time":"2007-04-21T16:47:44Z","timestamp":1177174064000},"page":"459-467","source":"Crossref","is-referenced-by-count":12,"title":["Respiratory cancer and other chronic disease mortality among silicotics in california"],"prefix":"10.1002","volume":"28","author":[{"given":"David F.","family":"Goldsmith","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James J.","family":"Beaumont","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynne A.","family":"Morrin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc B.","family":"Schenker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,19]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.2720"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00043764-199502000-00015"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.1720"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)43844-4"},{"key":"e_1_2_1_6_1","first-page":"433","article-title":"Silicosis: Cluster in sandblasters\u2014Texas and occupational surveillance for silicosis","volume":"39","author":"Fleming D","year":"1990","journal-title":"MMWR"},{"key":"e_1_2_1_7_1","first-page":"545","article-title":"Health effects of silica dust exposure","volume":"29","author":"Goldsmith DF","year":"1994","journal-title":"Rev Mineral"},{"key":"e_1_2_1_8_1","first-page":"245","volume-title":"Epidemiology of Lung Cancer","author":"Goldsmith DF","year":"1994"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700030408"},{"key":"e_1_2_1_10_1","volume-title":"Silica, Silicosis, and Cancer: Controversy in Occupational Medicine","author":"Goldsmith DF","year":"1986"},{"key":"e_1_2_1_11_1","unstructured":"GoldsmithDF BeaumontJJ MorrinLA SchenkerMB. (1994): Mortality among a registry of workers' compensation claimants for pulmonary diseases. 10th International Symposium on Epidemiology in Occupational Health Como Italy."},{"key":"e_1_2_1_12_1","first-page":"423","volume-title":"Silica, Silicosis, and Cancer: Controversy in Occupational Medicine","author":"Greenberg M","year":"1986"},{"key":"e_1_2_1_13_1","unstructured":"GuthrieGDJ HeaneyPJ. (1995): Mineralogical characteristics of the silica polymorphs in relation to their biological activities. Second International Symposium on Silica Silicosis and Cancer.Scand J Work Environ Health(in press)."},{"key":"e_1_2_1_14_1","first-page":"53","article-title":"Silica exposures, silicosis, and lung cancer: A mortality study of South African gold miners","volume":"48","author":"Hnizdo E","year":"1991","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700240408"},{"key":"e_1_2_1_16_1","volume-title":"IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Silica and Some Silicates","author":"IARC","year":"1987"},{"key":"e_1_2_1_17_1","first-page":"117","article-title":"Mortality from stomach cancer in Ontario miners","volume":"50","author":"Kusiak RA","year":"1993","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.2307\/2684614"},{"key":"e_1_2_1_19_1","first-page":"289","article-title":"Silica, silicosis and lung cancer (editorial) 46","volume":"46","author":"McDonald JC","year":"1989","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_20_1","volume-title":"Report to the Workers' Compensation Board on the Ontario Gold Mining Industry of the Scientific Panel on Mortality from Cancer Among Ontario Gold Miners 1955\u20101977","author":"Miller AB","year":"1987"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700170203"},{"key":"e_1_2_1_22_1","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1183\/09031936.93.04060730","article-title":"Silica and lung cancer: A controversial issue","volume":"4","author":"Pairon JC","year":"1991","journal-title":"Eur Respir J"},{"key":"e_1_2_1_23_1","volume-title":"Hunter's Diseases of Occupations","author":"Raffle PAB","year":"1987"},{"key":"e_1_2_1_24_1","volume-title":"Occupational Exposure to Silica and Cancer Risk","author":"Simonato L","year":"1990"}],"container-title":["American Journal of Industrial Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajim.4700280403","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajim.4700280403","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T02:52:07Z","timestamp":1698375127000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajim.4700280403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,10]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1995,10]]}},"alternative-id":["10.1002\/ajim.4700280403"],"URL":"https:\/\/doi.org\/10.1002\/ajim.4700280403","archive":["Portico"],"relation":{},"ISSN":["0271-3586","1097-0274"],"issn-type":[{"value":"0271-3586","type":"print"},{"value":"1097-0274","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,10]]}}}