{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T13:34:41Z","timestamp":1767706481396},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2002,6,26]],"date-time":"2002-06-26T00:00:00Z","timestamp":1025049600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[2002,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Known brain manifestations of tuberous sclerosis (TSC) are cortical sclerotic tubera, giant cell astrocytomas, subependymal calcified nodules in the lateral walls of the lateral ventricles, and white matter heterotopias. In addition, small cyst\u2010like lesions in the white matter have been described. We report on three TSC patients with hitherto undescribed large cyst\u2010like cerebral lesions in subcortical and white matter locations. We emphasize that cystoid brain degeneration is a rare but typical cerebral manifestation of TSC and suggest that, in patients with such lesions, TSC should be taken into consideration. \u00a9 2002 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.10637","type":"journal-article","created":{"date-parts":[[2002,9,5]],"date-time":"2002-09-05T20:26:02Z","timestamp":1031257562000},"page":"435-439","source":"Crossref","is-referenced-by-count":23,"title":["Cyst\u2010like cerebral lesions in tuberous sclerosis"],"prefix":"10.1002","volume":"111","author":[{"given":"Hans\u2010Dieter","family":"Rott","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beate","family":"Lemcke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Zenker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Huk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00fcrgen","family":"Horst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"Mayer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,6,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002470050573"},{"key":"e_1_2_5_3_1","first-page":"81","article-title":"Scl\u00e9rose tub\u00e9reuse des circonvolution sc\u00e9r\u00e9brales: idiotie et \u00e9pilepsie h\u00e9mipl\u00e9gique","volume":"1","author":"Bourneville DM","year":"1880","journal-title":"Arch Neurol (Paris)"},{"key":"e_1_2_5_4_1","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1080\/02841859809172211","article-title":"White matter abnormalities in tuberous sclerosis complex","volume":"39","author":"Griffith PD","year":"1998","journal-title":"Acta Radiologica"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1067\/mva.2001.111976"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.35.8.1223"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00341739"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02012989"},{"key":"e_1_2_5_9_1","first-page":"453","volume-title":"Paediatric neurology","author":"Neville BGR","year":"1993"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.158.6.1590106"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/13816819009015713"},{"key":"e_1_2_5_12_1","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1093\/oso\/9780195122107.003.0009","volume-title":"Tuberous sclerosis complex","author":"Scheitauer BW","year":"1999"},{"key":"e_1_2_5_13_1","first-page":"752","article-title":"Les phakomatoses de Bourneville, de Recklinghausen and de von Hippel\u2010Lindau","volume":"33","author":"Van der Hoeve J","year":"1933","journal-title":"J Belge Neurol Psychiat"},{"key":"e_1_2_5_14_1","first-page":"1367","article-title":"Cystic like white matter lesions in tuberous sclerosis","volume":"18","author":"Van Tassel P","year":"1997","journal-title":"Am J Neuroradiol"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-199011000-00021"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.10637","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.10637","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T11:22:53Z","timestamp":1700392973000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.10637"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,6,26]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2002,9]]}},"alternative-id":["10.1002\/ajmg.10637"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.10637","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,6,26]]}}}