{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:07:46Z","timestamp":1792166866373,"version":"4.4.0"},"reference-count":4,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,6,2]],"date-time":"2005-06-02T00:00:00Z","timestamp":1117670400000},"content-version":"vor","delay-in-days":9649,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1979,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a stillborn girl with a complex syndrome of microcephaly, lissencephaly, severe subcutaneous edema, atrophic muscles, camptodactyly, syndactyly of toes and fingers, hypoplastic genitalia, and numerous structural changes of the brain and eyes. Similar cases have been reported by Neu et al [1], Laxova et al [2] and Povy\u0161ilova et al [3]. The above\u2010mentioned syndrome complex is a distinct genetic syndrome, for which we propose the eponym \u201cthe Neu\u2010Laxova syndrome.\u201d Affected patients resemble each other strikingly and there is usually no doubt about the diagnosis. The Neu\u2010Laxova syndrome is apparently transmitted as an autosomal recessive trait.<\/jats:p>","DOI":"10.1002\/ajmg.1320030304","type":"journal-article","created":{"date-parts":[[2005,6,12]],"date-time":"2005-06-12T00:41:04Z","timestamp":1118536864000},"page":"261-267","source":"Crossref","is-referenced-by-count":47,"title":["The Neu\u2010Laxova syndrome\u2014a distinct entity"],"prefix":"10.1002","volume":"3","author":[{"given":"Gennady I.","family":"Lazjuk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iosif W.","family":"Lurie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa I.","family":"Ostrowskaja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugeny D.","family":"Cherstvoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irena A.","family":"Kirillova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael K.","family":"Nedzved","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergei S.","family":"Usoev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M.","family":"Optiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,6,2]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1542\/peds.47.3.610","article-title":"A lethal syndrome of microcephaly with multiple congenital anomalies in three siblings","volume":"47","author":"Neu RL","year":"1971","journal-title":"Pediatrics"},{"key":"e_1_2_1_3_2","first-page":"139","article-title":"A further example of a lethal autosomal recessive condition in sibs","volume":"16","author":"Laxova R","year":"1972","journal-title":"J Ment Defic Res"},{"key":"e_1_2_1_4_2","first-page":"190","article-title":"Let\u00e1lni syndrom mnoho\u010detn\u00fdch malformaci u t\u0159i sourozenc\u00fa","volume":"31","author":"Pov\u0301y\u0161ilov\u00e1 V","year":"1976","journal-title":"\u010cesk Pediatr"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1977.tb07973.x"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320030304","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320030304","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T23:37:07Z","timestamp":1699832227000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320030304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,1]]},"references-count":4,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1979,1]]}},"alternative-id":["10.1002\/ajmg.1320030304"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320030304","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,1]]}}}