{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:43:58Z","timestamp":1762505038644},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,6,2]],"date-time":"2005-06-02T00:00:00Z","timestamp":1117670400000},"content-version":"vor","delay-in-days":8402,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1982,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Peyronie's disease, a connective tissue disorder of unknown cause, is characterized by the formation of thickened fibrous plaques on the dorsum of the penis. It often occurs simultaneously with other fibrotic changes, most notably Dupuytren's contracture of the hands or feet. There are no previous reports suggesting inheritance of this syndrome; however, Willscher et al reported an association between Peyronie's disease and antigens of the HLA\u2010B7 cross\u2010reacting group.<\/jats:p><jats:p>Family studies were undertaken when three patients reported similarly affected first\u2010degree relatives. One kindred showed father\u2010to\u2010son transmission of Peyronie's disease with Dupuytren's contracture in three generations. Pedigree analysis of the three families suggests that Peyronie's syndrome is a male\u2010limited, automosal\u2010dominant trait. Antigens of the HLA\u2010B7 cross\u2010reacting group occurred in all three kindreds; however, the data ruled out close linkage of the disease and HLA.<\/jats:p>","DOI":"10.1002\/ajmg.1320120213","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T18:42:26Z","timestamp":1118515346000},"page":"227-235","source":"Crossref","is-referenced-by-count":52,"title":["Peyronie's disease: A newly recognized autosomal\u2010dominant trait"],"prefix":"10.1002","volume":"12","author":[{"given":"Wilma B.","family":"Bias","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Leroy M.","family":"Nyberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc C.","family":"Hochberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick C.","family":"Walsh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John M.","family":"Opitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,2]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"193","article-title":"Crossreactive HLA antigens in B27\u2010negative Reiter's syndrome and sacroiliitis","volume":"141","author":"Arnett FC","year":"1997","journal-title":"Johns Hopkins Med J"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(73)91360-3"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365597609179648"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1975.tb03950.x"},{"key":"e_1_2_1_6_1","unstructured":"LeffellMS DevineCJJr HortonCE SomersKD RoweMJ Vande BergJS BlueminkGG DawsonD WrightGL(1981):An analysis of histocompatibility antigens in association with Peyronie's disease. Program 76th Ann Mtg Am Urol Assoc May 10\u201314 1981 Boston p151."},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.45B4.709"},{"key":"e_1_2_1_8_1","first-page":"695","article-title":"The prevalence of Dupuytren's disease in Norway","volume":"138","author":"Mikkelsen OA","year":"1972","journal-title":"Acta Chir Scand"},{"key":"e_1_2_1_9_1","first-page":"318","article-title":"Sur quelques obstacles qui s'opposent \u00e0 l'\u00e9jaculation naturelle de la semence","author":"Peyronie de la F","year":"1743","journal-title":"M\u00e9m de l'Acad Roy de Chir"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197304052881403"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)56238-2"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320120213","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320120213","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T02:11:53Z","timestamp":1699841513000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320120213"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,6]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1982,6]]}},"alternative-id":["10.1002\/ajmg.1320120213"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320120213","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,6]]}}}