{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T20:09:02Z","timestamp":1768075742398,"version":"3.49.0"},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,6,3]],"date-time":"2005-06-03T00:00:00Z","timestamp":1117756800000},"content-version":"vor","delay-in-days":8130,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1983,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We present two sisters whose malformations (hydrocephalus, cystic dysplasia of the kidneys, polydactyly, and cleft palate) are consistent with a diagnosis of the Meckel syndrome. Diagnosis in case 1 was delayed because of two factors: (1) prolonged survival (28 mo), and (2) the absence of severe craniofacial malformations. These two factors may create difficulties in making this diagnosis and result in uncertainty regarding the medical prognosis of the infant and the genetic prognosis for the parents.<\/jats:p>","DOI":"10.1002\/ajmg.1320140303","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T15:34:47Z","timestamp":1118504087000},"page":"417-421","source":"Crossref","is-referenced-by-count":32,"title":["Survival and spectrum of anomalies in the meckel syndrome"],"prefix":"10.1002","volume":"14","author":[{"given":"R. Brian","family":"Lowry","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert H.","family":"Hill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bluma","family":"Tischler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,3]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"277","article-title":"Five month extrauterine survival in a female triploid (69,XXX) child","volume":"20","author":"Cassidy SB","year":"1977","journal-title":"Ann Genet"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320090112"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00443506"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320050205"},{"key":"e_1_2_1_6_1","first-page":"167","article-title":"Syndrome de Meckel: Genealogie inhabituelle","volume":"27","author":"Malpuech G","year":"1979","journal-title":"J Genet Hum"},{"key":"e_1_2_1_7_1","first-page":"97","article-title":"Encephalocele, polycystic kidneys, and polydactyly as an autosomal recessive trait simulating certain other disorders: The Meckel syndrome","volume":"14","author":"Mecke S","journal-title":"Ann Genet"},{"key":"e_1_2_1_8_1","volume-title":"Malformation Syndromes, Part II","author":"Opitz JM","year":"1969"},{"issue":"2","key":"e_1_2_1_8_2","first-page":"167","author":"The National Foundation\u2014March of Dimes","journal-title":"BD:OAS"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320050408"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1981.tb01811.x"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320140303","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320140303","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T20:14:56Z","timestamp":1697746496000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320140303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,3]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1983,3]]}},"alternative-id":["10.1002\/ajmg.1320140303"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320140303","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,3]]}}}