{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T05:21:04Z","timestamp":1697865664988},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,6,2]],"date-time":"2005-06-02T00:00:00Z","timestamp":1117670400000},"content-version":"vor","delay-in-days":8037,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1983,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We describe the clinical and hematological findings in a 5\u2010year\u2010old boy with G\u03b3 A\u03b3 \u03b4\u03b2 thalassemia, a G\u03b3 A\u03b3 heterocellular form of HPFH, \u03b2\u00ba thalassemia, and albinism. Clinically he manifested only the characteristics of \u03b2\u2010thalassemia trait and not the typical picture of doubly heterozygous \u03b2 thal\/\u03b4\u03b2 thal. The simultaneous presence of heterocellular HPFH improves \u03b3 chain synthesis, thus reducing the \u03b1 chain excess. It is also possible that gene expression can be modified by the presence of other genetic anomalies.<\/jats:p>","DOI":"10.1002\/ajmg.1320150206","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T15:39:26Z","timestamp":1118504366000},"page":"225-231","source":"Crossref","is-referenced-by-count":2,"title":["Unusual combination of genetic defects in a Sicilian boy: G\u03b3 A\u03b3 \u03b4\u03b2 thalassemia, G\u03b3 A\u03b3 heterocellular HPFH, \u03b2\u00ba thalassemia, and albinism"],"prefix":"10.1002","volume":"15","author":[{"given":"G.","family":"Schilir\u00f2","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Pavone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. 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