{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T15:43:45Z","timestamp":1764171825621},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,6,3]],"date-time":"2005-06-03T00:00:00Z","timestamp":1117756800000},"content-version":"vor","delay-in-days":7946,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1983,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A healthy normally intelligent man and his two daughters who had mild developmental delay and different malformations were determined to have an acrocentric supernumerary microchromosome (MC). The father and both daughters were noted to be mosaic for the MC, perhaps suggesting mitotic instability of the MC cell line with loss over time. The MC was negative staining on G\u2010banding and showed absence of centromeric heterochromatin on C\u2010banding. A centromere was identified with silver staining; no NORs were identified. The MC approximated the size of the short arm of the Y chromosome and showed cytologic behavior similar to that of a Y chromosome. H\u2010Y antigen and Y\u2010DNA gene probe studies failed to confirm a Yp origin.<\/jats:p>","DOI":"10.1002\/ajmg.1320160114","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T18:55:51Z","timestamp":1118516151000},"page":"89-97","source":"Crossref","is-referenced-by-count":9,"title":["Familial supernumerary microchromosome mosaicism: Phenotypic effects and an attempt at characterization"],"prefix":"10.1002","volume":"16","author":[{"given":"Albert E.","family":"Chudley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huui\u2010Zu","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulino D.","family":"Pabello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Shia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsi\u2010Chang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John M.","family":"Opitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,3]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"485","article-title":"The implications of detecting an extra metacentric microchromosome on amniotic fluid cell culture","volume":"58","author":"Barnard AH","year":"1980","journal-title":"S Afr Med J"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.15.2.136"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-1809.1980.tb01556.x"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/BF00277634","article-title":"Complete deficiency of constitutive heterochromatin on a human chromosome 9","volume":"49","author":"Buys CHCM","year":"1979","journal-title":"Hum Genet"},{"key":"e_1_2_1_6_1","first-page":"119A","article-title":"Three generation transmission of mosaicism for a small supernumerary marker chromosome","volume":"34","author":"Byrne JLB","year":"1982","journal-title":"Am J Hum Genet"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/298682a0"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.18.3.161"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1139\/g80-061"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00291577"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320050403"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01997700"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.929180"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1980.tb00882.x"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.18.5.392"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.17.1.48"},{"key":"e_1_2_1_17_1","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1093\/oxfordjournals.jhered.a109197","article-title":"Assignment of the H\u2010Y antigen gene to the short arm of chromosome Y","volume":"70","author":"Rary JM","year":"1979","journal-title":"J Hered"},{"key":"e_1_2_1_18_1","first-page":"458","article-title":"Sexual and somatic determinants of the human Y chromosome: Studies in a 46,XYp \u2010 phenotypic female","volume":"31","author":"Rosenfeld RG","year":"1979","journal-title":"Am J Hum Genet"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1979.tb00840.x"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1977.tb00942.x"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00569714"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1980.tb00159.x"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320160114","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320160114","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T11:45:46Z","timestamp":1697802346000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320160114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,9]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1983,9]]}},"alternative-id":["10.1002\/ajmg.1320160114"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320160114","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,9]]}}}