{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T05:31:21Z","timestamp":1700544681439},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,6,3]],"date-time":"2005-06-03T00:00:00Z","timestamp":1117756800000},"content-version":"vor","delay-in-days":7824,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1984,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Dermatoglyphics of 39 males with the fragile\u2010X syndrome were compared with those of 3 groups of control subjects; 497 school boys, 15 males with non\u2010specific mental retardation, and 15 with Down syndrome. Compared with the control males, there was an increased frequency of radial loops, whorls, and arches on the fingers and of third interdigital patterns and abnormal creases on the hands, and a decreased frequency of ulnar loops and fourth interdigital patterns in the patients with the fragile\u2010X syndrome. The mean <jats:styled-content>a\u2010b<\/jats:styled-content> ridge count was lower than in controls and there were more patients than controls with an <jats:styled-content>a\u2010b<\/jats:styled-content> ridge count &lt; 70. All of these differences were significant at p &lt; 0.01. There was no difference between patients and controls with respect to total ridge count on the fingers and the dermatoglyphics in other areas of the hands or feet.<\/jats:p><jats:p>From this small study a preliminary index was developed that attempts to distinguish male patients with the fragile\u2010X syndrome from normal male controls and males with nonfragile\u2010X forms of mental retardation. The patterns on the left and right third fingers, the <jats:styled-content>a\u2010b<\/jats:styled-content> ridge count, and the palmar creases were used in the index. Sixty\u2010four % of patients with the fragile\u2010X syndrome would be selected out if \u2265 + 0.5 was used as the criterion and 90% of these males would be expected to have the fragile\u2010X chromosome.<\/jats:p>","DOI":"10.1002\/ajmg.1320170112","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T19:00:44Z","timestamp":1118516444000},"page":"195-207","source":"Crossref","is-referenced-by-count":14,"title":["Fragile\u2010X syndrome III: Dermatoglyphic studies in males"],"prefix":"10.1002","volume":"17","author":[{"given":"Nancy E.","family":"Simpson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. J.","family":"Newman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. 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