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Aneuploidy: 47,XXX; 47,XX, +marker; and 45,X\/46,XX\/47,XXX were found in the other 3 women. The overall aberration frequency was 2.2% of couples. When a stringent criterion of \u2265 3 consecutive spontaneous abortions was used, the frequency was 4.2%. In this series no chromosome aberrations were identified in couples with 2 spontaneous abortions and a live\u2010born child with congenital anomalies; 1 of 22 couples with 2 spontaneous abortions and a still\u2010born infant showed a chromosomal abnormality. Findings from the recent literature are compared with those from this study.<\/jats:p>","DOI":"10.1002\/ajmg.1320170310","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T19:38:39Z","timestamp":1118518719000},"page":"615-620","source":"Crossref","is-referenced-by-count":10,"title":["Cytogenetic findings in 318 couples with repeated spontaneous abortion: A review of experience in British Columbia"],"prefix":"10.1002","volume":"17","author":[{"given":"J. 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