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These methods are relatively simple and can easily be applied for routine examinations of all women at risk of being a Hunter heterozygote. These results permit for the first time meaningful genetic counseling for the families of Hunter patients.<\/jats:p>","DOI":"10.1002\/ajmg.1320170317","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T19:38:39Z","timestamp":1118518719000},"page":"661-665","source":"Crossref","is-referenced-by-count":21,"title":["Heterozygote detection in hunter syndrome"],"prefix":"10.1002","volume":"17","author":[{"given":"Jo\u00ebl","family":"Zlotogora","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gideon","family":"Bach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,6,3]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(81)90274-6"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.70.7.2134"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1542\/peds.53.3.396","article-title":"Demonstration of the heterozygous state in Hunter's syndrome","volume":"53","author":"Booth CW","year":"1974","journal-title":"Pediatrics"},{"key":"e_1_2_1_5_1","first-page":"7","article-title":"Separation of leukocytes from blood and bone marrow","volume":"21","author":"Boyum A","year":"1968","journal-title":"Scand J Clin Lab Invest"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01920795"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1542\/peds.56.3.429","article-title":"Reliability of the Booth\u2010Nadler technique for the detection of Hunter heterozygotes","volume":"56","author":"Donnelly PV","year":"1975","journal-title":"Pediatrics"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)90027-1"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0076-6879(78)50048-7"},{"key":"e_1_2_1_10_1","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1203\/00006450-197608000-00007","article-title":"Iduronate sulfatase activity in serum, lymphocytes, and fibroblasts simplified diagnosis of Hunter syndrome","volume":"10","author":"Liebaers I","year":"1976","journal-title":"Pediatr Res"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)52451-6"},{"key":"e_1_2_1_12_1","first-page":"751","volume-title":"The Metabolic Basis of Inherited Disease","author":"McKusick VA","year":"1982"},{"key":"e_1_2_1_13_1","first-page":"448","article-title":"X\u2010linked Hunter syndrome: The heterozygous phenotype in cell culture","volume":"29","author":"Migeon BR","year":"1977","journal-title":"Am J Hum Genet"},{"key":"e_1_2_1_14_1","first-page":"42","article-title":"Detection of Hunter heterozygotes by enzymatic analysis of hair roots","volume":"31","author":"Nwokoro N","year":"1979","journal-title":"Am J Hum Genet"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00295699"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00569706"},{"key":"e_1_2_1_17_1","first-page":"575","article-title":"Iduronate sulfatase analysis of hair roots for identification of Hunter syndrome heterozygotes","volume":"30","author":"Yutaka T","year":"1978","journal-title":"Am J Hum Genet"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320170317","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320170317","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T20:33:48Z","timestamp":1697747628000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320170317"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,3]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1984,3]]}},"alternative-id":["10.1002\/ajmg.1320170317"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320170317","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,3]]}}}