{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:19:18Z","timestamp":1760782758788},"reference-count":6,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,6,3]],"date-time":"2005-06-03T00:00:00Z","timestamp":1117756800000},"content-version":"vor","delay-in-days":7672,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1984,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Two unrelated infants with delayed development and suspected abnormalities of the upper limbs were found to have the Coffin\u2010Lowry syndrome. Both had marked fullness of the forearms in the presence of normal skeletal structures which resulted from increased subcutaneous fat. Although initially misleading, the forearm changes may serve as an early diagnostic clue in this disorder.<\/jats:p>","DOI":"10.1002\/ajmg.1320180203","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T19:42:31Z","timestamp":1118518951000},"page":"195-199","source":"Crossref","is-referenced-by-count":13,"title":["Forearm fullness in Coffin\u2010Lowry syndrome: A misleading yet possible early diagnostic clue"],"prefix":"10.1002","volume":"18","author":[{"given":"Joseph H.","family":"Hersh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"Weisskopf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Crystal","family":"DeCoster","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John M.","family":"Opitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,3]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"205","article-title":"Mental retardation with osteocartilaginous anomalies","volume":"112","author":"Coffin GS","year":"1966","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1982.tb01379.x"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1973.tb01143.x"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.100.1.80"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1971.02100170078009"},{"issue":"6","key":"e_1_2_1_7_1","first-page":"133","article-title":"The Coffin Lowry syndrome. A simply inherited trait comprising mental retardation, facio\u2010digital anomalies and skeletal involvement","author":"Temtamy SA","year":"1975","journal-title":"Birth Defects"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320180203","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320180203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T12:47:09Z","timestamp":1697806029000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320180203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,6]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1984,6]]}},"alternative-id":["10.1002\/ajmg.1320180203"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320180203","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,6]]}}}