{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T13:19:48Z","timestamp":1767705588858},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,6,8]],"date-time":"2005-06-08T00:00:00Z","timestamp":1118188800000},"content-version":"vor","delay-in-days":7190,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1985,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report on three sibs with right\u2010sided microtia, meatal atresia, and conductive deafness. Two of the sibs also had right\u2010sided palatoplegia. These sibs may have the autosomal\u2010recessive form of microtia (No. 25180, McKusick [1983]), of which few familial cases are known to date. The malformation is due to a disturbance of the development of the first and second branchial arches. Review of the literature shows that microtia and meatal atresia with or without middle\u2010ear involvement are developmental field defects which, either isolated or as a part of the facio\u2010auriculovertebral spectrum, may occur (1) sporadically, (2) as component manifestation of syndromes, (3) as a multifactorial, or (4) as an apparent Mendelian trait.<\/jats:p>","DOI":"10.1002\/ajmg.1320220216","type":"journal-article","created":{"date-parts":[[2005,9,6]],"date-time":"2005-09-06T13:17:38Z","timestamp":1126012658000},"page":"327-332","source":"Crossref","is-referenced-by-count":21,"title":["Familial microtia, meatal atresia, and conductive deafness in three siblings"],"prefix":"10.1002","volume":"22","author":[{"given":"M.","family":"Schmid","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Schr\u00f6der","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Langenbeck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John M.","family":"Opitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James F.","family":"Reynolds","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,8]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.10.3.305-a"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.5.4.289"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1978.tb02110.x"},{"key":"e_1_2_1_5_1","first-page":"588","article-title":"Congenital aural atresia: An analysis of 311 cases","volume":"80","author":"Jafek BW","year":"1975","journal-title":"Trans Am Acad Ophthalmol Otolaryngol"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1972.00770090179002"},{"key":"e_1_2_1_7_1","volume-title":"Mendelian Inheritance in Man: Catalogs of Autosomal Dominant, Autosomal Recessive, and X\u2010linked Phenotypes","author":"McKusick VA","year":"1983"},{"issue":"4","key":"e_1_2_1_8_1","first-page":"35","article-title":"Congenital aural atresia: Anatomy and surgical management","author":"Nager GT","year":"1971","journal-title":"Birth Defects"},{"key":"e_1_2_1_9_1","first-page":"165","article-title":"Essai d'une nosologie g\u00e9n\u00e9tique de l'atresia auris congenita","volume":"30","author":"Pfeiffer RA","year":"1982","journal-title":"J Genet Hum"},{"key":"e_1_2_1_10_1","volume-title":"The First Conference on the Clinical Delineation of Birth Defects. Part II, Malformation Syndromes","author":"Pruzansky S","year":"1969"},{"issue":"2","key":"e_1_2_1_10_2","first-page":"120","journal-title":"BD:OAS"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320150207"},{"key":"e_1_2_1_12_1","volume-title":"Recognizable Patterns of Human Malformation: Genetic, Embryologic and Clinical Aspects","author":"Smith DW","year":"1982"},{"key":"e_1_2_1_13_1","first-page":"96","volume-title":"The Deaf Child","author":"Whetnall E","year":"1964"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1979.tb01011.x"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320220216","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320220216","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T00:30:25Z","timestamp":1695774625000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320220216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,10]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1985,10]]}},"alternative-id":["10.1002\/ajmg.1320220216"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320220216","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,10]]}}}