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At necropsy she was found to have a right spleen and right pulmonary isomerism (three lobes in each lung, as commonly found in the asplenia syndrome). This observation, together with other literature reports, suggest that isolated dextrocardia, situs viscerum inversus, and the asplenia\u2010poly\u2010splenia complex may be different end results of a unique dysmorphogenetic process involving the embryonic midline.<\/jats:p>","DOI":"10.1002\/ajmg.1320270420","type":"journal-article","created":{"date-parts":[[2005,6,12]],"date-time":"2005-06-12T02:58:55Z","timestamp":1118545135000},"page":"929-934","source":"Crossref","is-referenced-by-count":21,"title":["Dextrocardia with and without situs viscerum inversus in two sibs"],"prefix":"10.1002","volume":"27","author":[{"given":"Giuseppe","family":"Distefano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario G.","family":"Romeo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastiano","family":"Grasso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Mazzone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Sciacca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florindo","family":"Mollica","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Neri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,9]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(61)80059-0"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320160107"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(77)80476-9"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320210125"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM190711141572004"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(80)90388-9"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.59.3.242"},{"key":"e_1_2_1_9_1","first-page":"344","article-title":"Familial polysplenia and cardiovascular defects (Abstr)","volume":"13","author":"Hallett JJ","year":"1979","journal-title":"Pediatr Res"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1982.tb01402.x"},{"key":"e_1_2_1_11_1","first-page":"35","article-title":"Famili\u00e4res Asplenie\u2010syndrom","volume":"19","author":"J\u00f2j\u00e0rt G","year":"1978","journal-title":"Acta Paediatr Acad Sci Hung"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.65.3.633"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.2183\/pjab.56.633"},{"key":"e_1_2_1_14_1","series-title":"BD:OAS","first-page":"277","volume-title":"Heart malformations in mice homozygous for a gene causing situs inversus","author":"Layton WM","year":"1978"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1982.tb01425.x"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320160108"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320210126"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320120408"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.9.6.696"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.37.8.840"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(64)90454-0"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80439-3"},{"key":"e_1_2_1_23_1","first-page":"636","article-title":"Syndrome of spleen agenesis, defects of the heart and vessels and situs inversus. 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