{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:30:27Z","timestamp":1770823827700,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,6,5]],"date-time":"2005-06-05T00:00:00Z","timestamp":1117929600000},"content-version":"vor","delay-in-days":5999,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1989,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report herein bilateral small kidneys found in a mother and her two sons. This was associated with slowly progressive chronic renal failure. None of the patients had any of the associated clinical manifestations of recognized syndromes in which there is autosomal dominant inheritance of bilateral small kidneys (e.g., branchio\u2010oto\u2010renal syndrome). Nor did they have the clinical symptoms commonly associated with medullary cystic kidney\u2010juvenile nephronophthisis. However, there were some manifestations that have been reported in familial hypoplastic kidneys with glomerular cysts. Without wanting to claim that this is a \u201cnew\u201d syndrome, we are, however, unaware of any reports describing a similar kindred. The importance of this report stems mainly from the fact that a woman with mild to moderate stable chronic renal failure associated with, or caused by, bilateral small dysplastic kidneys gave birth to two sons with the same problem.<\/jats:p>","DOI":"10.1002\/ajmg.1320320126","type":"journal-article","created":{"date-parts":[[2005,6,12]],"date-time":"2005-06-12T03:26:04Z","timestamp":1118546764000},"page":"120-126","source":"Crossref","is-referenced-by-count":6,"title":["Autosomal dominant inheritance of small kidneys"],"prefix":"10.1002","volume":"32","author":[{"given":"Bernard S.","family":"Kaplan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence S.","family":"Milner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sigrid","family":"Jequier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paige","family":"Kaplan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Pierre","family":"De Chadarevian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John M.","family":"Opitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James F.","family":"Reynolds","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,5]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320190407"},{"key":"e_1_2_1_3_1","first-page":"A45","article-title":"Autosomal dominant hypoplastic glomerulocystic kidney disease","volume":"41","author":"Barratt TM","year":"1987","journal-title":"Clin Genet"},{"key":"e_1_2_1_4_1","volume-title":"Pediatric Kidney Disease","author":"Bernstein J","year":"1988"},{"key":"e_1_2_1_5_1","first-page":"335","volume-title":"Contemporary Issues in Nephrology, Tubulointerstitial Nephropathies","author":"Bernstein J","year":"1983"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00440537"},{"key":"e_1_2_1_7_1","first-page":"1","article-title":"Juvenile nephronophthisis and medullary cystic disease \u2013 The same disease (report of a large family with medullary cystic disease associated with gout and epilepsy)","volume":"18","author":"Burke JR","year":"1982","journal-title":"Clin Nephrol"},{"key":"e_1_2_1_8_1","first-page":"377","article-title":"Familial renal agenesis and total dysplasia","volume":"128","author":"Cain DR","year":"1974","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_9_1","first-page":"83","article-title":"Bilateral renal dysplasia in three siblings. Report of a survivor","volume":"5","author":"Cole BR","year":"1976","journal-title":"Clin Nephrol"},{"key":"e_1_2_1_10_1","first-page":"1","article-title":"Malformations of kidney and urinary tract in common chromosomal aberrations. I. Clinical studies","volume":"18","author":"Egli F","year":"1973","journal-title":"Humangenetik"},{"key":"e_1_2_1_11_1","first-page":"1536","article-title":"Severe renal dysgenesis produced by a dominant gene","volume":"130","author":"Fitch N","year":"1976","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1976.tb01546.x"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.37.5.494"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(84)80366-2"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1984.tb09946.x"},{"key":"e_1_2_1_16_1","first-page":"263","article-title":"Familial hypoplastic glomerulocystic kidney. 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