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This may represent a spurious association or genetic heterogeneity vis\u2010a\u2010vis the reported linkage of KS to the steroid sulphatase gene on the X chromosome. The pathophysiology and genetics of KS are discussed.<\/jats:p>","DOI":"10.1002\/ajmg.1320350303","type":"journal-article","created":{"date-parts":[[2005,6,12]],"date-time":"2005-06-12T03:45:23Z","timestamp":1118547923000},"page":"306-309","source":"Crossref","is-referenced-by-count":20,"title":["Chromosome abnormality in Kallmann syndrome"],"prefix":"10.1002","volume":"35","author":[{"given":"Lyle G.","family":"Best","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter A.","family":"Wasdahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda M.","family":"Larson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Sturlaugson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,5]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00291422"},{"key":"e_1_2_1_3_1","series-title":"BD:OAS","first-page":"175","volume-title":"The Clinical Delineation of Birth Defects, The Endocrine System","author":"Bardin WC","year":"1971"},{"key":"e_1_2_1_4_1","first-page":"576","volume-title":"Principles and Practice of Medical Genetics","author":"Cohen MM","year":"1983"},{"key":"e_1_2_1_5_1","first-page":"309","article-title":"\u00c9tudes sur les dysraphies cr\u01cenioenc\u00e9phaliques. 1 Ag\u00e9n\u00e9sie des lobes olfactifs (t\u00e9lenc\u00e9phaloschizis lat\u00e9ral) et des commissures calleuse et ant\u00e9rieure (t\u00e9lenc\u00e9phaloschizis m\u00e9dian). 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