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They also present clinically with an intestinal obstruction that proves fatal within the first few days of life. The LWFS involves both melanocytes and intestinal ganglion cells, and appears to result from a genetic defect involving neural crest cells. This report describes pathologic studies of two recent cases of LWFS. Two different hypothetical models of inheritance of LWFS are presented and discussed.<\/jats:p>","DOI":"10.1002\/ajmg.1320360319","type":"journal-article","created":{"date-parts":[[2005,6,12]],"date-time":"2005-06-12T00:48:30Z","timestamp":1118537310000},"page":"336-340","source":"Crossref","is-referenced-by-count":56,"title":["Overo lethal white foal syndrome: Equine model of aganglionic megacolon (Hirschsprung disease)"],"prefix":"10.1002","volume":"36","author":[{"given":"Linda","family":"McCabe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa D.","family":"Griffin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Kinzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marge","family":"Chandler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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