{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:28:03Z","timestamp":1787243283008,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,6,3]],"date-time":"2005-06-03T00:00:00Z","timestamp":1117756800000},"content-version":"vor","delay-in-days":4933,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1991,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Direct two\u2010generation transmission of an unbalanced 18p + chromosome was discovered after amniocentesis. Neither the mother nor the child exhibited apparent physical malformations or mental impairment. Banding analysis suggested a complete 18p duplication. Molecular studies verified the 18p origin of the duplicated material. Only 14 previous cases of duplication 18p have been reported and these exhibited either a normal phenotype or mild and inconsistent abnormalities. The present cases, as well as the review of literature, indicate that duplication 18p is associated with few or inapparent phenotypic abnormalities.<\/jats:p>","DOI":"10.1002\/ajmg.1320410311","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T23:47:06Z","timestamp":1118533626000},"page":"319-321","source":"Crossref","is-referenced-by-count":48,"title":["Prenatal ascertainment of an inherited dup(18p) associated with an apparently normal phenotype"],"prefix":"10.1002","volume":"41","author":[{"given":"Daynna J.","family":"Wolff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie J.","family":"Raffel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merry M.","family":"Ferr\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,6,3]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"428","article-title":"Molecular analysis of the human X\u2010chromosome (HGM 7)","volume":"37","author":"Bruns G","year":"1984","journal-title":"Cytogenet Cell Genet"},{"key":"e_1_2_1_3_1","unstructured":"DallapiccolaB ForaboscoL ZelanteA NotarangeloG PerlaS CalvanoS NeriC: (1986):The 18ph + chromosome heteromorphism. 7th Int Cong Hum Genet Berlin Abstr Part I:81\u201382."},{"key":"e_1_2_1_4_1","first-page":"132A","article-title":"Is 18ph + a normal chromosomal variant?","volume":"35","author":"Fordyce RR","year":"1983","journal-title":"Am J Hum Genet"},{"key":"e_1_2_1_5_1","volume-title":"Sex Differentiation and Chromosomal Abnormalities","author":"Gardner RJM","year":"1978"},{"issue":"6","key":"e_1_2_1_5_2","first-page":"359","author":"The National Foundation\u2013March of Dimes","journal-title":"BD:OAS"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.20.5.377"},{"key":"e_1_2_1_7_1","first-page":"144","article-title":"Chromosome 18 abnormalities in a family with a translocation t(18p\u2010;21p + )","volume":"12","author":"Jacobsen P","year":"1968","journal-title":"J Ment Defic Res"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320290418"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00293038"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1034517"},{"key":"e_1_2_1_11_1","first-page":"1221","article-title":"Due casi di sindrome 18p\u2010 ed un caso di trisomia 18p in una stessa fratria","volume":"197","author":"Rosano M","year":"1977","journal-title":"Neuropsych Infant"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(75)80083-0"},{"key":"e_1_2_1_13_1","first-page":"92A","article-title":"Recombinant chromosome 18 in two male sibs with first and second branchial arch syndrome","volume":"33","author":"Sujansky E","year":"1981","journal-title":"Am J Hum Genet"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.26.3.195"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1975.tb01515.x"},{"key":"e_1_2_1_16_1","volume-title":"The Cytogenetics of Mammalian Autosomal Rearrangements","author":"Van Dyke DL","year":"1988"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320410311","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320410311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T22:00:30Z","timestamp":1698012030000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320410311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,12]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1991,12]]}},"alternative-id":["10.1002\/ajmg.1320410311"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320410311","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,12]]}}}