{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T12:44:07Z","timestamp":1698583447690},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,6,3]],"date-time":"2005-06-03T00:00:00Z","timestamp":1117756800000},"content-version":"vor","delay-in-days":4902,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1992,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A series of 77 Swedish females with classical Rett syndrome were genealogically traced as far back as possible, in most cases to 1720\u20131750, or 7\u201310 generations. Details were collected concerning approximately 8,000 ancestors. Common ancestry was seen in 2 pairs of females with Rett syndrome. Thirty\u2010nine of the 77 Rett females were traced to 9 small and separate rural areas, and 17 pairs even came from the same farm or homestead. The common origin was found equally often among descendants of the father as of the mother. In 9 cases, the father came from one and the mother from another of the 9 specific \u201cRett areas.\u201d These observations, combined with the finding of a raised rate of consanguineous marriages in the paternal as well as in the maternal ancestry, point to a genetic transmission. Analyses of parental ages at birth and of birth order gave normal results.<\/jats:p>","DOI":"10.1002\/ajmg.1320420121","type":"journal-article","created":{"date-parts":[[2005,6,12]],"date-time":"2005-06-12T04:33:06Z","timestamp":1118550786000},"page":"104-108","source":"Crossref","is-referenced-by-count":17,"title":["Rett syndrome: A search for gene sources"],"prefix":"10.1002","volume":"42","author":[{"given":"Hans Olof","family":"\u00c5kesson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bengt","family":"Hagberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Wahlstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingegerd Witt","family":"Engerstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,3]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"295","article-title":"First\u2010cousin marriages in Sweden 1750\u20131844 and a study of the population movement in some Swedish subpopulations from the genetic\u2010statistical viewpoint","volume":"8","author":"Alstr\u00f6m CH","year":"1958","journal-title":"Acta Genet (Basel)"},{"key":"e_1_2_1_3_1","first-page":"61","article-title":"A clinical and genetic study of anencephaly","volume":"2","author":"B\u00f6\u00f6k JA","year":"1950","journal-title":"Am J Hum Genet"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0887-8994(89)90031-3"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410140412"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320250506"},{"key":"e_1_2_1_7_1","unstructured":"HagbergB Engerstr\u00f6mI Witt (1990) Swedish Rett syndrome basic data register 1960\u201390. In appendix to: Witt Engerstr\u00f6m I: Rett syndrome in Sweden.Acta Paediatr Scand Suppl 369."},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410230432"},{"key":"e_1_2_1_9_1","first-page":"107","article-title":"Neurofibromatosis in Sweden. IV. Genetic analyses","volume":"2","author":"Samuelsson B","year":"1989","journal-title":"Neurofibromatosis"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0387-7604(87)80065-7"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320420121","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320420121","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T13:49:01Z","timestamp":1698068941000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320420121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1992,1]]}},"alternative-id":["10.1002\/ajmg.1320420121"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320420121","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,1]]}}}