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One infant had AFA alone, one had Hay\u2013Wells syndrome, characterized by ectodermal dysplasia, and the other 2 had chromosome abnormalities, trisomy 18, and complex chromosome rearrangement, with visceral malformations. Despite heterogeneity and phenotypic variability, these developmental abnormalities shared (1) involvement of tissues growing in apposition and (2) temporal overlap of their occurrence. This suggests a common defect in the mechanism(s) that regulate tissue fusion at multiple sites during development.<\/jats:p>","DOI":"10.1002\/ajmg.1320420324","type":"journal-article","created":{"date-parts":[[2005,6,12]],"date-time":"2005-06-12T04:33:16Z","timestamp":1118550796000},"page":"369-373","source":"Crossref","is-referenced-by-count":28,"title":["Ankyloblepharon filiforme adnatum"],"prefix":"10.1002","volume":"42","author":[{"given":"Avery H.","family":"Weiss","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gisele","family":"Riscile","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boris G.","family":"Kousseff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,3]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.63.2.129"},{"key":"e_1_2_1_3_1","first-page":"869","volume-title":"System in Ophthalmology","author":"Duke\u2010Elder S","year":"1983"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1970.tb03745.x"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1242\/dev.99.3.285","article-title":"Embryonic induction\u2010molecular prospects","volume":"99","author":"Gurdon JB","year":"1987","journal-title":"Development"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1976.tb04384.x"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.58.6.630"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(77)90679-1"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(57)91522-2"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320260403"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(62)90409-9"},{"key":"e_1_2_1_12_1","first-page":"71","volume-title":"Mendelian Inheritance of Man","author":"McKusick VA","year":"1990"},{"key":"e_1_2_1_13_1","first-page":"149","volume-title":"The Developing Human","author":"Moore KL","year":"1973"},{"key":"e_1_2_1_14_1","first-page":"1","volume-title":"Biomedical Foundations of Ophthalmology","author":"Ozanics V","year":"1987"},{"key":"e_1_2_1_15_1","first-page":"175","article-title":"Role of epidermal growth factor in embryonic development","volume":"22","author":"Pratt RM","year":"1987","journal-title":"Dev Biol"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.72.3.874"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1961.01840020116019"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1980.02130200021008"},{"key":"e_1_2_1_19_1","first-page":"429","article-title":"Ankyloblepharon filiforme adnatum","volume":"2","author":"Von Hasner","year":"1881","journal-title":"Z Augenh, Prague"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320420324","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320420324","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T06:09:24Z","timestamp":1698127764000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320420324"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,2]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1992,2]]}},"alternative-id":["10.1002\/ajmg.1320420324"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320420324","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,2]]}}}