{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:14:04Z","timestamp":1763036044591},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,6,7]],"date-time":"2005-06-07T00:00:00Z","timestamp":1118102400000},"content-version":"vor","delay-in-days":4724,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1992,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We have studied three children with cutaneous (epidermal nevi), subcutaneous (lipomas, plantar skin thikening), vascular (hemangioma, lymphangioma), skeletal (osteoma, exostosis, localized hypertrophy), and neurological (hydrocephaly, lissencephaly, partial agenesis of the corpus callosum) developmental defects associated with the Proteus syndrome and related hamartoneoplastic conditions. We compared our findings in these three patients with those of 50 others with Proteus syndrome and nine with encephalocraniocutaneous lipomatosis (ECCL) reported in the literature. We found that Proteus syndrome and ECCL have distinct identities even though some clinical manifestations are shared by both and a few patients have manifestations of both conditions. \u00a9 1992 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.1320430403","type":"journal-article","created":{"date-parts":[[2005,6,12]],"date-time":"2005-06-12T04:43:49Z","timestamp":1118551429000},"page":"662-668","source":"Crossref","is-referenced-by-count":65,"title":["Encephalocraniocutaneous lipomatosis and the Proteus syndrome: Distinct entities with overlapping manifestations"],"prefix":"10.1002","volume":"43","author":[{"given":"Sherman","family":"McCall","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magda I.","family":"Ramzy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel K.","family":"Cure","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. S.","family":"Pai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00445918"},{"key":"e_1_2_1_3_1","first-page":"1085","article-title":"Picture of the month: Encephalocraniocutaneous lipomatosis","volume":"136","author":"Bitoun P","year":"1982","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/088307388700200301"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320270111"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1542\/peds.61.4.580","article-title":"Encephalocraniocutaneous lipomatosis","volume":"61","author":"Fishman MA","year":"1978","journal-title":"Pediatrics"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/088307388700200303"},{"key":"e_1_2_1_8_1","first-page":"361","volume-title":"Syndromes of the Head and Neck","author":"Gorlin RJ","year":"1990"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1970.00480200050005"},{"key":"e_1_2_1_10_1","first-page":"87","article-title":"Proteus syndrome and hamartoses with overgrowth","volume":"4","author":"Hotamisligil GS","year":"1990","journal-title":"Dysmorph Clin Genet"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1990.tb03562.x"},{"key":"e_1_2_1_12_1","first-page":"1418","volume-title":"Birth Defects Encyclopedia","author":"Kouseff BG","year":"1990"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320270112"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320320327"},{"key":"e_1_2_1_15_1","first-page":"280","article-title":"Encephalocranicutaneous lipomatosis: A recently described neurocutaneous syndrome","volume":"11","author":"Miyao M","year":"1984","journal-title":"Child's Brain"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1981.tb01717.x"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(85)90132-6"},{"key":"e_1_2_1_18_1","first-page":"235","article-title":"Encephalocraniocutane Lipomatose und linearer Naevus sebaceus","volume":"133","author":"Schlack HG","year":"1985","journal-title":"Mschr Kinderheilk"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320270110"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00661895"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320250229"},{"key":"e_1_2_1_22_1","first-page":"724","article-title":"Asymmetrical osteocutaneous lipomatosis in a three\u2010year\u2010old boy associated with defective development of the brain","volume":"38","author":"Zuntova A","year":"1983","journal-title":"Cs Pediatr"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320430403","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320430403","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T00:13:22Z","timestamp":1695860002000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320430403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,7]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1992,7]]}},"alternative-id":["10.1002\/ajmg.1320430403"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320430403","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,7]]}}}