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The pattern of associated malformations in infants with anencephaly and sirenomelia is reviewed. This condition, which combines cephalic and caudal defects of the embryo, could be considered an example of the \u201caxial mesodermal dysplasia spectrum\u201d and may be related to the midline developmental field concept. \u00a9 1992 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.1320430416","type":"journal-article","created":{"date-parts":[[2005,6,12]],"date-time":"2005-06-12T04:43:49Z","timestamp":1118551429000},"page":"732-736","source":"Crossref","is-referenced-by-count":21,"title":["Craniorachischisis totalis and sirenomelia"],"prefix":"10.1002","volume":"43","author":[{"given":"Jos\u00e9 Ignacio","family":"Rodr\u00edguez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Palacios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,7]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"197","article-title":"Anencefalia in sirenide","author":"Battaglia S","year":"1954","journal-title":"Fol Hered Pathol"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320360314"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320100105"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.20.5.338"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0028-2243(84)90040-6"},{"key":"e_1_2_1_7_1","first-page":"96","article-title":"Sirenomelia and VATER association: Possible interrelated disorders with common embryonic pathogenesis","volume":"2","author":"Duncan PA","year":"1988","journal-title":"Dysmorph Clin Genet"},{"key":"e_1_2_1_8_1","first-page":"574","volume-title":"Smith's Recognizable Patterns of Human Malformation","author":"Jones KL","year":"1988"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420090113"},{"key":"e_1_2_1_10_1","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1542\/peds.84.2.266","article-title":"Association of selected midline defects: A population study","volume":"84","author":"Khoury MJ","year":"1989","journal-title":"Pediatrics"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320280506"},{"key":"e_1_2_1_12_1","first-page":"159","volume-title":"Handbook of Clinical Neurology, Vol 32, Congenital Malformations of the Spine and SpinalCord","author":"Martin\u2010Padilla M","year":"1978"},{"key":"e_1_2_1_13_1","first-page":"145","article-title":"Frecuencia de los defectos cong\u00e9nitos en Espa\u00f1a: 1976\u20131983","volume":"25","author":"Mart\u00ednez\u2010Fr\u00edas ML","year":"1986","journal-title":"An Esp Pediatr"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320260406"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320170210"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420400502"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320120408"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420380517"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320390107"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420320305"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(79)80278-4"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420340303"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.78.3.451"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320210121"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.3109\/15513818609068846"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320430416","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320430416","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T00:12:54Z","timestamp":1695859974000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320430416"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,7]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1992,7]]}},"alternative-id":["10.1002\/ajmg.1320430416"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320430416","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,7]]}}}