{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:26:28Z","timestamp":1786976788071,"version":"build-2736575974"},"reference-count":9,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2005,6,3]],"date-time":"2005-06-03T00:00:00Z","timestamp":1117756800000},"content-version":"vor","delay-in-days":4689,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1992,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We report on 12 Brazilian boys with the Opitz G\/BBB syndrome associated with CNS midline anomalies, namely, Dandy\u2010Walker anomaly (two patients), enlarged cisterna magna (four patients), enlarged 4th ventricle (four patients), and callosal a\/hypoplasia (two patients). These signs clearly show the involvement of the CNS midline in the Opitz G\/BBB syndrome. \u00a9 1992 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.1320430603","type":"journal-article","created":{"date-parts":[[2005,6,12]],"date-time":"2005-06-12T00:52:08Z","timestamp":1118537528000},"page":"918-928","source":"Crossref","is-referenced-by-count":29,"title":["CNS midline anomalies in the opitz G\/BBB syndrome: Report on 12 Brazilian patients"],"prefix":"10.1002","volume":"43","author":[{"given":"M. L.","family":"Guion\u2010Almeida","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Richieri\u2010Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,6,3]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320280207"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320020205"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320280204"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320280203"},{"key":"e_1_2_1_6_1","first-page":"72A","article-title":"Features of the G (Opitz\u2010Frias) and BBB (hypospadias hypertelorism) syndrome in one family: Are they a single disorder?","volume":"390","author":"Parisian S","year":"1978","journal-title":"Am J Hum Genet"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1975.tb00325.x"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320340303"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320280206"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320290417"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320430603","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320430603","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T06:53:51Z","timestamp":1698044031000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320430603"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,8]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1992,8]]}},"alternative-id":["10.1002\/ajmg.1320430603"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320430603","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,8]]}}}