{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:28:21Z","timestamp":1761974901540},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,6,7]],"date-time":"2005-06-07T00:00:00Z","timestamp":1118102400000},"content-version":"vor","delay-in-days":4648,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1992,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 3\u2010year\u2010old Libyan boy with the XXXXY syndrome is described. MRI examination of the brain showed hypoplasia of the corpus callosum. He had growth retardation and endocrine studies demonstrated growth hormone (GH) deficiency. Dermatoglyphic pattern was different from previous reports. At histological examination of the undescended testes, Leydig cells were seen although they are usually not found in this variant of the Klinefelter syndrome. \u00a9 1992 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.1320440221","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T16:21:30Z","timestamp":1118506890000},"page":"230-232","source":"Crossref","is-referenced-by-count":13,"title":["Hypoplasia of the corpus callosum and growth hormone deficiency in the XXXXY syndrome"],"prefix":"10.1002","volume":"44","author":[{"given":"Gabriele","family":"Haeusler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Frisch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.","family":"Guchev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Hadziselimovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Neuhold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Vormittag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,7]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"473","article-title":"Is hyperploidy of sex chromosomes associated with reduced finger ridge count?","volume":"17","author":"Alter M","year":"1965","journal-title":"Am J Hum Genet"},{"key":"e_1_2_1_3_1","first-page":"487","article-title":"Normal postnatal development of the corpus callosum as demonstrated by MR imaging","volume":"9","author":"Barkovich AJ","year":"1987","journal-title":"AJNR"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","DOI":"10.1097\/00000441-195909000-00030","volume-title":"Radiographic Atlas of the Development of the Hand and Wrist","author":"Greulich WW","year":"1959"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0387-7604(87)80042-6"},{"key":"e_1_2_1_6_1","first-page":"339","article-title":"MR imaging of callosal and corticocallosal dysgenesis","volume":"10","author":"Jinkins JR","year":"1989","journal-title":"AJNR"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00540236"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320130320"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/197933a0"},{"key":"e_1_2_1_10_1","first-page":"869","article-title":"Ein Patient mit XXXXY Chromosomen","volume":"16","author":"Schade H","year":"1963","journal-title":"Med Welt"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-51620-7"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1052407"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00440360"},{"key":"e_1_2_1_14_1","first-page":"1563","article-title":"Het XXXXY syndroom","volume":"109","author":"van Went JJ","year":"1965","journal-title":"Ned T Geneesk"},{"key":"e_1_2_1_15_1","first-page":"1143","article-title":"The XXXXY chromosome anomaly\u2014report of three new cases and review of 30 cases of the literature","volume":"94","author":"Zaleski WA","year":"1966","journal-title":"Can Med Assoc J"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320440221","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320440221","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T13:57:08Z","timestamp":1698069428000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320440221"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,9,15]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1992,9,15]]}},"alternative-id":["10.1002\/ajmg.1320440221"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320440221","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,9,15]]}}}