{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T04:06:35Z","timestamp":1788408395729,"version":"build-2803163510"},"reference-count":12,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2005,6,7]],"date-time":"2005-06-07T00:00:00Z","timestamp":1118102400000},"content-version":"vor","delay-in-days":4571,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1992,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We describe a 3\u2010generation family in which mother, maternal grandfather, and 2 (male and female) children have variably manifestations of the ulnar\u2010mammary syndrome, including ulnar ray defects, obesity, hypogenitalism, delayed puberty, hypoplasia of nipples and apocrine glands, and a previously undescribed ectopia of upper canines. The index patient also had split\u2010hand appearance on the right due to complete absence of the 4th ray. To our knowledge this is the first documented example of split hand in the ulnar\u2010mammary syndrome. The hand anomaly raises the question of a possible causal relationship between ulnar\u2010mammary syndrome and the split hand with aplasia of the ulna syndrome, as already hypothesized by Lenz [1980]. \u00a9 1992 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.1320440618","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T16:38:31Z","timestamp":1118507911000},"page":"807-812","source":"Crossref","is-referenced-by-count":19,"title":["Possible relationship between ulnar\u2010mammary syndrome and split hand with aplasia of the ulna syndrome"],"prefix":"10.1002","volume":"44","author":[{"given":"P.","family":"Franceschini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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Catalogs of Autosomal Dominant, Autosomal Recessive, and X\u2010linked phenotypes","author":"McKusick VA","year":"1975"},{"key":"e_1_2_1_9_1","first-page":"61","article-title":"Normal hands and feet in the ulnar\u2010mammary syndrome","volume":"3","author":"Meinecke P","year":"1989","journal-title":"Dysmorph Clin Genet"},{"issue":"5","key":"e_1_2_1_10_1","first-page":"247","article-title":"Studies of malformation syndromes in man XXXXII: a pleiotropic dominant mutation affecting skeletal, sexual and apocrine\u2010mammary development","author":"Pallister PD","year":"1976","journal-title":"BDOAS"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.24.12.778"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1987.tb03347.x"},{"issue":"3","key":"e_1_2_1_13_1","first-page":"51","article-title":"The genetics of hand malformations","author":"Temtamy SA","year":"1978","journal-title":"BDOAS"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320440618","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320440618","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T13:37:43Z","timestamp":1698154663000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320440618"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,12]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1992,12]]}},"alternative-id":["10.1002\/ajmg.1320440618"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320440618","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,12]]}}}