{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T21:04:56Z","timestamp":1792184696923,"version":"4.4.0"},"reference-count":7,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,6,7]],"date-time":"2005-06-07T00:00:00Z","timestamp":1118102400000},"content-version":"vor","delay-in-days":4526,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1993,1,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Children with osteogenesis imperfecta (OI) that results in considerable deformity are often viewed as poor candidates for aggressive physical therapy and rehabilitation. To determine if this view is realistic, we have entered almost 50 children with OI type III and OI type IV into a comprehensive graduated rehabilitation program, based at the National Institutes of Health, but designed to be implemented by continuing involvement of community resources. Children are begun in the program early with emphasis on gain of head and trunk control and progression to sitting and walking, if possible, with the aid of a variety of phsysical supports, including internal and external bracing. Although not conducted in a randomized fashion, the program's success in bringing children into graded exercise regimes and fostering their increased involvement in school and social situations suggest that aggressive physical therpy and rehabilitation have a major place in the overall care of the infants and children with OI.<\/jats:p>","DOI":"10.1002\/ajmg.1320450224","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T12:39:13Z","timestamp":1118493553000},"page":"265-269","source":"Crossref","is-referenced-by-count":36,"title":["Comprehensive rehabilitation of the child with osteogenesis imperfecta"],"prefix":"10.1002","volume":"45","author":[{"given":"Helga","family":"Binder","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Conway","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Hason","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn H.","family":"Gerber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Marini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger","family":"Berry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Weintrob","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,6,7]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"537","article-title":"Osteogenesis imperfecta: Rehabilitation approach with infants and young children","volume":"65","author":"Binder H","year":"1984","journal-title":"Arch Phys Med Rehabil"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1097\/00003086-198109000-00015","article-title":"Nonoperative treatment of osteogenesis imperfecta: Orthotic and mobility management","volume":"159","author":"Bleck EE","year":"1981","journal-title":"Clin Orthop Rel Res"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1097\/00003086-199002000-00043","article-title":"Rehabilitation of children and infants with osteogenesis imperfecta. A program for ambulation","volume":"251","author":"Gerber LH","year":"1990","journal-title":"Clin Orthop Rel Res"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01241398-198807000-00014"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/17453678208992255"},{"key":"e_1_2_1_7_1","first-page":"977","article-title":"Psychosocial aspects of osteogenesis imperfecta","volume":"135","author":"Shea\u2010Landry GL","year":"1986","journal-title":"CMNJ"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.16.2.101"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320450224","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320450224","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T15:45:21Z","timestamp":1698162321000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320450224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,1,15]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1993,1,15]]}},"alternative-id":["10.1002\/ajmg.1320450224"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320450224","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,1,15]]}}}