{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T04:09:08Z","timestamp":1792382948368,"version":"4.4.0"},"reference-count":4,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,6,7]],"date-time":"2005-06-07T00:00:00Z","timestamp":1118102400000},"content-version":"vor","delay-in-days":4389,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1993,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We describe a 4\u2010year\u2010old boy with an interstitial deletion of the long arm of chromosome 10:del(10) (q11.2q22.1). Frontal bossing, hypertelorism, bright blue iris color, up\u2010slanting palpebral fissures, a flat nasal bridge, a broad nose, apparently low\u2010set ears, micrognathia, deep philtrum, and hypotonia were noted neonatally. A murmur was noted at age 5\u00bd months and surgical repair of subaortic stenosis was required at 4 years. At 4 years micrognathia was no longer evident, but the palate was high\u2010arched. The pattern of abnormalities included postnatal\u2010onset slow growth, short stature, mental retardation, and cardiac anomalies. \u00a9 1993 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.1320460418","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T16:28:22Z","timestamp":1118507302000},"page":"438-440","source":"Crossref","is-referenced-by-count":5,"title":["Interstitial deletion of chromosome 10, del(10) (q11.2q22.1) in a boy with developmental delay and multiple congenital anomalies"],"prefix":"10.1002","volume":"46","author":[{"given":"Julie L.","family":"Zenger\u2010Hain","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacquelyn","family":"Roberson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel L.","family":"Van Dyke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lester","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,6,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320430410"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.850784"},{"key":"e_1_2_1_4_1","first-page":"A154","article-title":"Chromosome rearrangements localizing the chromosome 10 loci RBP3 and D10S5","volume":"43","author":"Norum RA","year":"1988","journal-title":"Am J Hum Genet"},{"issue":"2","key":"e_1_2_1_5_1","first-page":"339","article-title":"Refined localization to contiguous regions on chromosome 10q of the two genes (H4 and RET) that form the oncogenic sequence PTC","volume":"6","author":"Sozzi G","year":"1991","journal-title":"Oncogene"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320460418","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320460418","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T05:27:27Z","timestamp":1698298047000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320460418"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,6]]},"references-count":4,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1993,6]]}},"alternative-id":["10.1002\/ajmg.1320460418"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320460418","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,6]]}}}