{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T05:43:15Z","timestamp":1770010995735,"version":"3.49.0"},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2005,6,3]],"date-time":"2005-06-03T00:00:00Z","timestamp":1117756800000},"content-version":"vor","delay-in-days":4371,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1993,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The cause of sudden infant death syndrome (SIDS) is unknown. Sleep\u2010related impairment of respiratory control and arousal are postulated; hyperdopaminergic and hyposerotonergic dysfunction may contribute to events leading to infant apnea and SIDS. Psychosocial adversity and impulsive and compulsive behaviours characterize some families of SIDS victims. Tourette syndrome (TS) is a common hereditary neurobehavioral disorder characterized by the frequent presence of impulsive and compulsive behaviors. Sleep disorders are common and include sleep apnea and abnormal arousal. Hyperdopaminergic and hyposerotonergic abnormalities are postulated to contribute to the pathophyusiology of the disorder. The following is a report of the presence of incidents of infant apnea and SIDS in families in which TS was present. In an additional TS family, a child had obstructive sleep apnea syndrome (OSAS). Results of a preliminary survey suggest that TS gene carriers are at increased risk of life\u2010threatening apneas of infancy and that the prevalence of SIDS in such families may be 2 to 5 times the prevalence in the general population. The presence in some pedigrees of sleep apnea in children and adults suggest that in some instances disorders of sleep\u2010related ventilatory control and arousal occurring throughout the life\u2010span share common pathophysiological mechanisms. \u00a9 1993 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.1320460506","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T16:59:31Z","timestamp":1118509171000},"page":"494-496","source":"Crossref","is-referenced-by-count":17,"title":["Is Tourette syndrome a cause of sudden infant death syndrome and childhood obstructive sleep apnea?"],"prefix":"10.1002","volume":"46","author":[{"given":"Jeffrey","family":"Sverd","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerardo","family":"Montero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,3]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"3","article-title":"Are there tests predictive for prolonged apnea and SIDS?","volume":"342","author":"Bentele KHP","year":"1988","journal-title":"Acta Pediatr Scand Suppl"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320390213"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","unstructured":"ComingDE ComingsBG(1993): SIDS and Tourette syndrome: Is there an etiological relationship?J Dev Physical Disabilities(in press).","DOI":"10.1007\/BF01047068"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02713925"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01377349"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.34.5.688"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100038087"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(84)80445-X"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-9877(85)90140-9"},{"key":"e_1_2_1_11_1","first-page":"47","volume-title":"Serotonin in Major Psychiatric Disorders","author":"McBride PA","year":"1990"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(76)80283-1"},{"key":"e_1_2_1_13_1","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1152\/jappl.1982.53.3.637","article-title":"Augmentation of ventilatory response to asphyxia by prochlorprazine in humans","volume":"53","author":"Olson LG","year":"1982","journal-title":"J Appl Physiol"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)90763-3"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198002283020903"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320390212"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80147-9"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320460506","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320460506","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T01:47:39Z","timestamp":1698284859000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320460506"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,6,15]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1993,6,15]]}},"alternative-id":["10.1002\/ajmg.1320460506"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320460506","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,6,15]]}}}