{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:00:04Z","timestamp":1787162404914,"version":"build-2736575974"},"reference-count":44,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,6,7]],"date-time":"2005-06-07T00:00:00Z","timestamp":1118102400000},"content-version":"vor","delay-in-days":4071,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1994,4,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We have observed a distinct form of \u201ccrossed\u201d polysyndactyly in 6 generations of a family with 5 affected persons, all males. The polydactyly is postaxial in the hands and preaxial in the feet. Syndactyly in the hands is observed in some relatives, while syndactyly in the feet is present bilaterally in all affected relatives. This seems to be an autosomal dominant trait with male to male transmission over 3 generations by examination and an additional 3 generations by history.<\/jats:p>\n                  <jats:p>This form of polysyndactyly could not be readily categorized by the existing classification by Temtamy and McKusick [1978: BD OAS XIV 6:363\u2013392]. We review and expand the present classification of polydactyly and syndactyly syndromes. \u00a9 1994 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.1320500302","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T13:06:51Z","timestamp":1118495211000},"page":"215-223","source":"Crossref","is-referenced-by-count":23,"title":["Familial crossed polysyndactyly"],"prefix":"10.1002","volume":"50","author":[{"given":"David J.","family":"Goldstein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marios","family":"Kambouris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard E.","family":"Ward","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,6,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00453148"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(77)80571-4"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.2106\/00004623-196446080-00006","article-title":"Cleft hand: classification, incidence, and treatment","volume":"46","author":"Barsky AJ","year":"1964","journal-title":"J Bone Joint Surg"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-1809.1930.tb02073.x"},{"key":"e_1_2_1_6_1","first-page":"187","article-title":"Die Gabelhand, Zugleich ein Beitrag zur Theorie der Missbildungen","volume":"3","author":"Bircher E","year":"1918","journal-title":"Bruns Beitr Clin Chir"},{"key":"e_1_2_1_7_1","first-page":"405","article-title":"Polydactyly: a genetic study in South America","volume":"25","author":"Castilla E","year":"1973","journal-title":"Am J Hum Genet"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00438491"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1000510205"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320380108"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1093\/oxfordjournals.jhered.a107368","article-title":"A family with polysyndactyly and other anomalies","volume":"56","author":"Goodman RM","year":"1965","journal-title":"J Hered"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320080213"},{"key":"e_1_2_1_13_1","first-page":"677","article-title":"Three\u2010phalangeal thumbs","volume":"42","author":"Haas SL","year":"1939","journal-title":"Am J Roentgenol Radium Ther Nucleic Med"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(40)90631-6"},{"key":"e_1_2_1_15_1","first-page":"237","article-title":"Fibula dimelia in association with ipsilateral proximal focal femoral deficiency, tibial deficiency, and polydactyly: A case report","volume":"258","author":"Igou RA","year":"1990","journal-title":"Clin Orthop"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320400108"},{"key":"e_1_2_1_17_1","first-page":"6","article-title":"Polydactyly of the foot: An unusual case presentation and review of the literature","volume":"39","author":"Jay RM","year":"1990","journal-title":"J Curr Podiat Med"},{"key":"e_1_2_1_18_1","first-page":"80","article-title":"Syndactyly of the ring and little finger","volume":"7","author":"Johnston O","year":"1955","journal-title":"Am J Hum Genet"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-197604000-00017"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1025321"},{"key":"e_1_2_1_21_1","first-page":"305","volume-title":"Lehrbuch der Rontgendiagnostik: II. 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