{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T05:17:37Z","timestamp":1718774257900},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,5,16]],"date-time":"2005-05-16T00:00:00Z","timestamp":1116201600000},"content-version":"vor","delay-in-days":3759,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1995,1,30]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Most individuals with the rare 46,XX male \u201csyndrome\u201d arise due to an unequal interchange between Xp and Yp termini during paternal meiosis. The pattern of Y\u2010sequences in these patients varies considerably, but very few cases have been reported showing only <jats:italic>SRY<\/jats:italic>. The phenotype in these patients is also variable ranging from severe impairment of the external genitalia through hypospadias and\/or cryptorchidism to occasional normal male phenotype.<\/jats:p><jats:p>We report a Mexican 46,XX male patient without genital ambiguities in whom DNA analysis showed the presence of <jats:italic>SRY<\/jats:italic> and the absence of <jats:italic>ZFY<\/jats:italic>. We conclude that in this case <jats:italic>SRY<\/jats:italic> alone was enough for complete male sexual differentiation. \u00a9 1995 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.1320550321","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T17:55:13Z","timestamp":1118512513000},"page":"356-358","source":"Crossref","is-referenced-by-count":8,"title":["<i>SRY<\/i> alone can induce normal male sexual differentiation"],"prefix":"10.1002","volume":"55","author":[{"given":"Marisol","family":"L\u00f3pez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leda","family":"Torres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan P.","family":"M\u00e9ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alicia","family":"Cervantes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo","family":"Alfaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregorio","family":"P\u00e9rez\u2010Palacios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert P.","family":"Erickson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susana","family":"Kofman\u2010Alfaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,5,16]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/14.13.5375"},{"key":"e_1_2_1_3_1","first-page":"1218","article-title":"End\u2010stage renal disease and primary hypogonadism associated with a 46, XX karyotype","volume":"146","author":"Bailey WA","year":"1992","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.24.10001"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000182319"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.0954-6820.1964.tb04630.x","article-title":"XX sex chromosomes in a human male. 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