{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T15:29:03Z","timestamp":1760887743076},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,5,16]],"date-time":"2005-05-16T00:00:00Z","timestamp":1116201600000},"content-version":"vor","delay-in-days":3577,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[1995,7,31]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A photoanthropometric method, which enables an objective description of facial structures, was used to better delineate the craniofacial characteristics of 37 individuals with Prader\u2010Willi syndrome (PWS; 21 males and 16 females; 22 with 15q11q13 deletions and 15 with normal\u2010appearing chromosome 15s) between the ages of 0 to 12 years. Facial parameters were measured from strict frontal and profile photographic 35 mm slides and compared with other facial measurements from the same face (e.g., palpebral fissure width to bizygomatic diameter). We studied 16 photoanthropometric craniofacial indices following the protocols established by Stengel\u2010Rutkowski et al. [1984: Hum Genet 67:272\u2013295] and Butler et al. [1988: Am J Med Genet 30:165\u2013168]. Based on our measurements of 37 Prader\u2010Willi syndrome individuals, none of the parameters were consistently outside of the normal range when compared with photoanthropometric index standards for age established from white control children [Stengel\u2010Rutkowski et al., 1984]. However, several suggestive findings were documented by our analysis including: narrow palpebral fissure width [particularly in older children (6\u201312 years)], high midface, broad interalar distance, short back of the nose, prominent high chin, and broad low\u2010set ears. No significant differences were found in craniofacial parameters between deletion or nondeletion Prader\u2010Willi syndrome patients with this methodology. These craniofacial parameters (many not previously evaluated in PWS patients) may become useful for early detection, and aid in the diagnosis and the study of the development of the characteristic face seen in Prader\u2010Willi patients. \u00a9 1995 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.1320580109","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T18:04:23Z","timestamp":1118513063000},"page":"38-45","source":"Crossref","is-referenced-by-count":16,"title":["Photoanthropometric study of craniofacial traits of individuals with Prader\u2010Willi syndrome"],"prefix":"10.1002","volume":"58","author":[{"given":"Merlin G.","family":"Butler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabrielle J.","family":"Levine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline Y.","family":"Le","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryan D.","family":"Hall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne B.","family":"Cassidy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,5,16]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"88","article-title":"Normative standards and patterning of fat and muscle in white and black newborn infants","volume":"5","author":"Brandt JM","year":"1991","journal-title":"Dysmorph Clin Genet"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320350306"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320300114"},{"key":"e_1_2_1_5_1","first-page":"853","article-title":"Standards for selected anthropometric measurements in Prader\u2010Willi syndrome","volume":"88","author":"Butler MG","year":"1991","journal-title":"Pediatrics"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320230307"},{"key":"e_1_2_1_7_1","first-page":"1217","article-title":"Clinical correlates of chromosome 15 deletions and maternal disomy in Prader\u2010Willi syndrome","volume":"147","author":"Lai LW","year":"1993","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199206113262404"},{"key":"e_1_2_1_9_1","first-page":"73","volume-title":"Vital and Health Statistics","author":"National Center for Health Statistics","year":"1973"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00291355"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1320580109","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.1320580109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T01:47:48Z","timestamp":1698284868000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1320580109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,7,31]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1995,7,31]]}},"alternative-id":["10.1002\/ajmg.1320580109"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.1320580109","archive":["Portico"],"relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,7,31]]}}}