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Using three highly polymorphic DNA markers (D21S212, PFKL, and D21S171) which flank the EPM1 locus, we performed linkage analysis to investigate whether or not the EPM1 gene is also implicated in Lafora disease. Linkage was excluded in three North\u2010African pedigrees each comprising at least two affected individuals. This result suggests that differential diagnosis of Lafora disease and Unverricht\u2010Lundborg disease may be facilitated by molecular genetic analysis. \u00a9 1995 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.1320600114","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T18:15:43Z","timestamp":1118513743000},"page":"80-84","source":"Crossref","is-referenced-by-count":0,"title":["Lafora disease is not linked to the Unverricht\u2010Lundborg 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